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Genetic Test For A Specific Gene Change

Missouri rates for HCPCS 81404

This is a laboratory test that analyzes a particular gene to look for a specific genetic change linked to an inherited condition or a disease risk. Which gene is examined depends on the medical reason the test was ordered, such as a family history of a certain condition or a diagnosis that needs genetic confirmation. The analysis involves techniques of moderate technical complexity compared with simpler single-variant genetic checks.

Rates data updated July 2026.

How much does Genetic Test For A Specific Gene Change cost?

$269

Typical negotiated rate. In Missouri, July 2026.

Insurers have agreed to pay about $269 for this service. The price depends on where it is billed: about $240 from a physician practice, and about $355 from a hospital or other facility. The two figures are alternatives, not parts of one bill.

These are rates insurers have negotiated with providers, not the amount a patient is billed. What you owe depends on your plan's deductible and coinsurance. Based on rates published by 6 insurance carriers under federal price transparency rules.

Where it's billed changes the price

Billed byTypicalRange
Physician practiceA doctor's office, clinic or independent provider$240$166 to $324
FacilityA hospital or hospital-owned outpatient department$355$269 to $479

How much rates vary

Facilitymedian $355 · 10th to 90th $100 to $631Professionalmedian $240 · 10th to 90th $110 to $537
$50$100$200$500$1Kfacility $355professional $240

Distribution of negotiated rates across all payers (price axis is log-scale). Each curve is scaled to its own total: facility and professional rates are different services, shown together to compare where they cluster. Need provider-level prices or 24+ months of history? Contact us.

Rates by insurance carrier

Insurance Carrier
Aetna
Setting
Facility
Modifier
Global
Typical Low
$63.10
Median
$436.52
Typical High
$537.03
Aetna
Setting
Professional
Modifier
Global
Typical Low
$234.42
Median
$269.15
Typical High
$562.34
Anthem BCBS
Setting
Facility
Modifier
Global
Typical Low
$275.42
Median
$275.42
Typical High
$954.99
Anthem BCBS
Setting
Professional
Modifier
Global
Typical Low
$60.26
Median
$218.78
Typical High
$478.63
BCBS
Setting
Facility
Modifier
Global
Typical Low
$380.19
Median
$407.38
Typical High
$707.95
BCBS
Setting
Professional
Modifier
Global
Typical Low
$190.55
Median
$275.42
Typical High
$309.03
Cigna
Setting
Facility
Modifier
Global
Typical Low
$208.93
Median
$537.03
Typical High
$851.14
Cigna
Setting
Professional
Modifier
Global
Typical Low
$125.89
Median
$213.80
Typical High
$398.11
Medica
Setting
Facility
Modifier
Global
Typical Low
$239.88
Median
$331.13
Typical High
$1,318.26
Medica
Setting
Professional
Modifier
Global
Typical Low
$114.82
Median
$165.96
Typical High
$1,380.38
United
Setting
Facility
Modifier
Global
Typical Low
$114.82
Median
$275.42
Typical High
$331.13
United
Setting
Professional
Modifier
Global
Typical Low
$114.82
Median
$165.96
Typical High
$371.54

Where Missouri sits

The same service costs 3.5 times more in Alaska than in Rhode Island. Every bar is a state, most expensive first. Touch or drag across it to read any state, then open that state for its carriers and full range.

Missouri· 25th of 51

$269

AK $617RI $174

Median negotiated rate in each state, from every insurer that publishes one. States where no insurer publishes a rate for this service are not shown.