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Genetic Test For A Specific Gene Change

Illinois rates for HCPCS 81404

This is a laboratory test that analyzes a particular gene to look for a specific genetic change linked to an inherited condition or a disease risk. Which gene is examined depends on the medical reason the test was ordered, such as a family history of a certain condition or a diagnosis that needs genetic confirmation. The analysis involves techniques of moderate technical complexity compared with simpler single-variant genetic checks.

Rates data updated October 2026.

How much does Genetic Test For A Specific Gene Change cost?

$214

Typical negotiated rate. In Illinois, October 2026.

Insurers have agreed to pay about $214 for this service. The price depends on where it is billed: about $191 from a physician practice, and about $513 from a hospital or other facility.

These are rates insurers have negotiated with providers, not the amount a patient is billed. What you owe depends on your plan's deductible and coinsurance. Based on rates published by 5 insurance carriers under federal price transparency rules.

Prices by location type

Billed byTypicalRange
Physician practiceA doctor's office, clinic or independent provider$191$3.80 to $214
FacilityA hospital or hospital-owned outpatient department$513$331 to $955

How much rates vary

Facilitymedian $513 · 10th to 90th $288 to $1,738Professionalmedian $191 · 10th to 90th $3 to $324
$10$100$1Kfacility $513professional $191

Distribution of negotiated rates across all payers (price axis is log-scale). Need provider-level prices or 24+ months of history? Contact us.

Rates by insurance carrier

Insurance Carrier
Aetna
Setting
Facility
Modifier
None
Typical Low
$223.87
Median
$426.58
Typical High
$831.76
Aetna
Setting
Professional
Modifier
None
Typical Low
$213.80
Median
$223.87
Typical High
$245.47
BCBS Illinois
Setting
Facility
Modifier
None
Typical Low
$331.13
Median
$478.63
Typical High
$3,467.37
BCBS Illinois
Setting
Professional
Modifier
None
Typical Low
$3.47
Median
$190.55
Typical High
$213.80
Cigna
Setting
Facility
Modifier
None
Typical Low
$295.12
Median
$575.44
Typical High
$1,148.15
Cigna
Setting
Professional
Modifier
None
Typical Low
$138.04
Median
$371.54
Typical High
$457.09
Hally Health
Setting
Professional
Modifier
None
Typical Low
$281.84
Median
$416.87
Typical High
$691.83
Hally Health
Setting
Facility
Modifier
None
Typical Low
$100.00
Median
$100.00
Typical High
$100.00
Hally Health
Setting
Professional
Modifier
None
Typical Low
$354.81
Median
$354.81
Typical High
$354.81
United
Setting
Facility
Modifier
None
Typical Low
$275.42
Median
$331.13
Typical High
$346.74
United
Setting
Professional
Modifier
None
Typical Low
$114.82
Median
$165.96
Typical High
$275.42
4 more rates with less common billing modifiers

A modifier changes what was billed, for example a reduced or repeated service. Each of these modifiers carries under 10% of the published rates for this code. Modifier combinations, and modifiers with fewer than 30 rates for a carrier, are not listed.

Insurance Carrier
Aetna
Setting
Facility
Modifier
52 · Reduced service
Typical Low
$112.20
Median
$213.80
Typical High
$416.87
Aetna
Setting
Facility
Modifier
53 · Discontinued
Typical Low
$44.67
Median
$85.11
Typical High
$165.96
Aetna
Setting
Professional
Modifier
52 · Reduced service
Typical Low
$109.65
Median
$112.20
Typical High
$123.03
Aetna
Setting
Professional
Modifier
53 · Discontinued
Typical Low
$43.65
Median
$44.67
Typical High
$48.98

Where Illinois sits

The same service costs 3.5 times more in Alaska than in Utah. Every bar is a state, most expensive first. Touch or drag across it to read any state, then open that state for its carriers and full range.

Illinois· 44th of 51

$214

AK $617UT $174

Median negotiated rate in each state, from every insurer that publishes one. States where no insurer publishes a rate for this service are not shown.