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Targeted Genetic Analysis of a Known Change

Missouri rates for HCPCS 81402

A laboratory analysis of DNA or RNA that checks a sample for specific, already-known genetic changes rather than reading a gene from end to end. Which gene is examined depends on the condition being investigated; services grouped together here share the amount and difficulty of the laboratory work rather than a single disease.

Rates data updated October 2026.

How much does Targeted Genetic Analysis of a Known Change cost?

$145

Typical negotiated rate. In Missouri, October 2026.

Insurers have agreed to pay about $145 for this service. The price depends on where it is billed: about $129 from a physician practice, and about $263 from a hospital or other facility.

These are rates insurers have negotiated with providers, not the amount a patient is billed. What you owe depends on your plan's deductible and coinsurance. Based on rates published by 6 insurance carriers under federal price transparency rules.

Prices by location type

Billed byTypicalRange
Physician practiceA doctor's office, clinic or independent provider$129$95.50 to $234
FacilityA hospital or hospital-owned outpatient department$263$158 to $457

How much rates vary

Facilitymedian $263 · 10th to 90th $135 to $891Professionalmedian $129 · 10th to 90th $74 to $380
$100$200$500$1Kfacility $263professional $129

Distribution of negotiated rates across all payers (price axis is log-scale). Need provider-level prices or 24+ months of history? Contact us.

Rates by insurance carrier

Insurance Carrier
Aetna
Setting
Facility
Modifier
None
Typical Low
$128.82
Median
$194.98
Typical High
$275.42
Aetna
Setting
Professional
Modifier
None
Typical Low
$117.49
Median
$128.82
Typical High
$158.49
Anthem BCBS
Setting
Facility
Modifier
None
Typical Low
$151.36
Median
$151.36
Typical High
$691.83
Anthem BCBS
Setting
Professional
Modifier
None
Typical Low
$100.00
Median
$125.89
Typical High
$269.15
BCBS Kansas City
Setting
Facility
Modifier
None
Typical Low
$208.93
Median
$234.42
Typical High
$407.38
BCBS Kansas City
Setting
Professional
Modifier
None
Typical Low
$104.71
Median
$151.36
Typical High
$288.40
Cigna
Setting
Facility
Modifier
None
Typical Low
$123.03
Median
$338.84
Typical High
$478.63
Cigna
Setting
Professional
Modifier
None
Typical Low
$70.79
Median
$144.54
Typical High
$194.98
Medica
Setting
Facility
Modifier
None
Typical Low
$134.90
Median
$263.03
Typical High
$891.25
Medica
Setting
Professional
Modifier
None
Typical Low
$75.86
Median
$154.88
Typical High
$758.58
United
Setting
Facility
Modifier
None
Typical Low
$134.90
Median
$134.90
Typical High
$134.90
United
Setting
Professional
Modifier
None
Typical Low
$63.10
Median
$91.20
Typical High
$204.17
2 more rates with less common billing modifiers

A modifier changes what was billed, for example a reduced or repeated service. Each of these modifiers carries under 10% of the published rates for this code. Modifier combinations, and modifiers with fewer than 30 rates for a carrier, are not listed.

Insurance Carrier
Aetna
Setting
Professional
Modifier
52 · Reduced service
Typical Low
$64.57
Median
$64.57
Typical High
$87.10
Aetna
Setting
Professional
Modifier
53 · Discontinued
Typical Low
$25.70
Median
$25.70
Typical High
$34.67

Where Missouri sits

The same service costs 5.4 times more in Alaska than in Alabama. Every bar is a state, most expensive first. Touch or drag across it to read any state, then open that state for its carriers and full range.

Missouri· 28th of 51

$145

AK $339AL $63.10

Median negotiated rate in each state, from every insurer that publishes one. States where no insurer publishes a rate for this service are not shown.