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Basic Single Gene Variant Test

Pennsylvania rates for HCPCS 81400

A genetic laboratory test that looks for one specific, well-established genetic change using a relatively simple laboratory technique. It represents the most basic tier of gene-based testing, generally used to check for a single known variant tied to a specific condition or trait rather than scanning a gene broadly. The exact gene and variant tested depends on why the test was ordered.

Rates data updated July 2026.

Facilitymedian $141 · 10th–90th $55$3160%10%20%10th90th$141Professionalmedian $55 · 10th–90th $50$1510%50%10th90th$55$50.0$200.0$1.0K$5.0K$20.0K

Distribution of negotiated rates across all payers (price axis is log-scale). Facility and professional rates are different services and are charted separately. Need provider-level prices? Contact us.

Insurance Carrier
Aetna
Setting
Facility
Modifier
Global
Typical Low
$54.95
Median
$141.25
Typical High
$281.84
Aetna
Setting
Professional
Modifier
Global
Typical Low
$51.29
Median
$54.95
Typical High
$229.09
Capital Blue Cross
Setting
Facility
Modifier
Global
Typical Low
$234.42
Median
$316.23
Typical High
$8,511.38
Capital Blue Cross
Setting
Professional
Modifier
Global
Typical Low
$50.12
Median
$50.12
Typical High
$50.12
Cigna
Setting
Facility
Modifier
Global
Typical Low
$61.66
Median
$104.71
Typical High
$218.78
Cigna
Setting
Professional
Modifier
Global
Typical Low
$33.88
Median
$67.61
Typical High
$144.54
Emblem Health
Setting
Professional
Modifier
Global
Typical Low
$44.67
Median
$44.67
Typical High
$83.18
Geisinger
Setting
Facility
Modifier
Global
Typical Low
$64.57
Median
$64.57
Typical High
$64.57
Geisinger
Setting
Professional
Modifier
Global
Typical Low
$47.86
Median
$83.18
Typical High
$141.25
Highmark BCBS
Setting
Facility
Modifier
Global
Typical Low
$134.90
Median
$588.84
Typical High
$645.65
Independence Blue Cross
Setting
Professional
Modifier
Global
Typical Low
$64.57
Median
$64.57
Typical High
$64.57
Martin's Point
Setting
Facility
Modifier
Global
Typical Low
$51.29
Median
$141.25
Typical High
$281.84
Martin's Point
Setting
Professional
Modifier
Global
Typical Low
$51.29
Median
$60.26
Typical High
$229.09
UPMC Health Plan
Setting
Facility
Modifier
Global
Typical Low
$144.54
Median
$199.53
Typical High
$416.87
UPMC Health Plan
Setting
Professional
Modifier
Global
Typical Low
$64.57
Median
$64.57
Typical High
$93.33
United
Setting
Facility
Modifier
Global
Typical Low
$57.54
Median
$64.57
Typical High
$77.62
United
Setting
Professional
Modifier
Global
Typical Low
$26.92
Median
$38.02
Typical High
$95.50