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Basic Single Gene Variant Test

Missouri rates for HCPCS 81400

A genetic laboratory test that looks for one specific, well-established genetic change using a relatively simple laboratory technique. It represents the most basic tier of gene-based testing, generally used to check for a single known variant tied to a specific condition or trait rather than scanning a gene broadly. The exact gene and variant tested depends on why the test was ordered.

Rates data updated October 2026.

How much does Basic Single Gene Variant Test cost?

$61.66

Typical negotiated rate. In Missouri, October 2026.

Insurers have agreed to pay about $61.66 for this service. The price depends on where it is billed: about $54.95 from a physician practice, and about $112 from a hospital or other facility.

These are rates insurers have negotiated with providers, not the amount a patient is billed. What you owe depends on your plan's deductible and coinsurance. Based on rates published by 6 insurance carriers under federal price transparency rules.

Prices by location type

Billed byTypicalRange
Physician practiceA doctor's office, clinic or independent provider$54.95$39.81 to $100
FacilityA hospital or hospital-owned outpatient department$112$67.61 to $182

How much rates vary

Facilitymedian $112 · 10th to 90th $58 to $302Professionalmedian $55 · 10th to 90th $32 to $166
$20$50$100$200$500facility $112professional $55

Distribution of negotiated rates across all payers (price axis is log-scale). Need provider-level prices or 24+ months of history? Contact us.

Rates by insurance carrier

Insurance Carrier
Aetna
Setting
Facility
Modifier
None
Typical Low
$54.95
Median
$83.18
Typical High
$117.49
Aetna
Setting
Professional
Modifier
None
Typical Low
$54.95
Median
$54.95
Typical High
$67.61
Anthem BCBS
Setting
Facility
Modifier
None
Typical Low
$64.57
Median
$64.57
Typical High
$295.12
Anthem BCBS
Setting
Professional
Modifier
None
Typical Low
$39.81
Median
$53.70
Typical High
$114.82
BCBS Kansas City
Setting
Facility
Modifier
None
Typical Low
$89.13
Median
$100.00
Typical High
$173.78
BCBS Kansas City
Setting
Professional
Modifier
None
Typical Low
$44.67
Median
$64.57
Typical High
$120.23
Cigna
Setting
Facility
Modifier
None
Typical Low
$52.48
Median
$144.54
Typical High
$204.17
Cigna
Setting
Professional
Modifier
None
Typical Low
$30.20
Median
$60.26
Typical High
$83.18
Medica
Setting
Facility
Modifier
None
Typical Low
$57.54
Median
$112.20
Typical High
$302.00
Medica
Setting
Professional
Modifier
None
Typical Low
$31.62
Median
$66.07
Typical High
$316.23
United
Setting
Facility
Modifier
None
Typical Low
$57.54
Median
$57.54
Typical High
$57.54
United
Setting
Professional
Modifier
None
Typical Low
$26.92
Median
$38.02
Typical High
$85.11
2 more rates with less common billing modifiers

A modifier changes what was billed, for example a reduced or repeated service. Each of these modifiers carries under 10% of the published rates for this code. Modifier combinations, and modifiers with fewer than 30 rates for a carrier, are not listed.

Insurance Carrier
Aetna
Setting
Professional
Modifier
52 · Reduced service
Typical Low
$26.92
Median
$27.54
Typical High
$37.15
Aetna
Setting
Professional
Modifier
53 · Discontinued
Typical Low
$10.96
Median
$10.96
Typical High
$14.79

Where Missouri sits

The same service costs 3.4 times more in Alaska than in Delaware. Every bar is a state, most expensive first. Touch or drag across it to read any state, then open that state for its carriers and full range.

Missouri· 32nd of 51

$61.66

AK $145DE $42.66

Median negotiated rate in each state, from every insurer that publishes one. States where no insurer publishes a rate for this service are not shown.