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Basic Single Gene Variant Test

Maryland rates for HCPCS 81400

A genetic laboratory test that looks for one specific, well-established genetic change using a relatively simple laboratory technique. It represents the most basic tier of gene-based testing, generally used to check for a single known variant tied to a specific condition or trait rather than scanning a gene broadly. The exact gene and variant tested depends on why the test was ordered.

Rates data updated October 2026.

How much does Basic Single Gene Variant Test cost?

$47.86

Typical negotiated rate. In Maryland, October 2026.

Insurers have agreed to pay about $47.86 for this service. Most negotiated rates run $42.66 to $51.29.

These are rates insurers have negotiated with providers, not the amount a patient is billed. What you owe depends on your plan's deductible and coinsurance. Based on rates published by 6 insurance carriers under federal price transparency rules.

How much rates vary

Professionalmedian $48 · 10th to 90th $29 to $65
$50$100professional $48

Distribution of negotiated rates across all payers (price axis is log-scale). Need provider-level prices or 24+ months of history? Contact us.

Rates by insurance carrier

Insurance Carrier
Aetna
Setting
Professional
Modifier
None
Typical Low
$47.86
Median
$47.86
Typical High
$58.88
CareFirst
Setting
Professional
Modifier
None
Typical Low
$45.71
Median
$51.29
Typical High
$54.95
Cigna
Setting
Professional
Modifier
None
Typical Low
$30.20
Median
$50.12
Typical High
$186.21
Kaiser Permanente
Setting
Professional
Modifier
None
Typical Low
$64.57
Median
$77.62
Typical High
$95.50
United
Setting
Professional
Modifier
None
Typical Low
$26.92
Median
$31.62
Typical High
$56.23
Wellpoint
Setting
Professional
Modifier
None
Typical Low
$51.29
Median
$51.29
Typical High
$51.29
2 more rates with less common billing modifiers

A modifier changes what was billed, for example a reduced or repeated service. Each of these modifiers carries under 10% of the published rates for this code. Modifier combinations, and modifiers with fewer than 30 rates for a carrier, are not listed.

Insurance Carrier
Aetna
Setting
Professional
Modifier
52 · Reduced service
Typical Low
$23.44
Median
$23.99
Typical High
$28.84
Aetna
Setting
Professional
Modifier
53 · Discontinued
Typical Low
$9.55
Median
$9.55
Typical High
$11.75

Where Maryland sits

The same service costs 3.4 times more in Alaska than in Delaware. Every bar is a state, most expensive first. Touch or drag across it to read any state, then open that state for its carriers and full range.

Maryland· 47th of 51

$47.86

AK $145DE $42.66

Median negotiated rate in each state, from every insurer that publishes one. States where no insurer publishes a rate for this service are not shown.