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High-Resolution Tissue-Type Test, Single Marker

Virginia rates for HCPCS 81381

This is a detailed genetic test that examines one specific immune-system marker gene at high resolution, most often used before a bone marrow, stem cell, or organ transplant to see how closely a donor's tissue type matches the recipient's. Fine-grained matching on these markers helps predict how well a transplant will be tolerated. The test is run on a blood sample.

Rates data updated October 2026.

How much does High-Resolution Tissue-Type Test, Single Marker cost?

$138

Typical negotiated rate. In Virginia, October 2026.

Insurers have agreed to pay about $138 for this service. The price depends on where it is billed: about $123 from a physician practice, and about $224 from a hospital or other facility.

These are rates insurers have negotiated with providers, not the amount a patient is billed. What you owe depends on your plan's deductible and coinsurance. Based on rates published by 8 insurance carriers under federal price transparency rules.

Prices by location type

Billed byTypicalRange
Physician practiceA doctor's office, clinic or independent provider$123$83.18 to $158
FacilityA hospital or hospital-owned outpatient department$224$170 to $398

How much rates vary

Facilitymedian $224 · 10th to 90th $166 to $832Professionalmedian $123 · 10th to 90th $68 to $240
$20$100$500$2K$10Kfacility $224professional $123

Distribution of negotiated rates across all payers (price axis is log-scale). Need provider-level prices or 24+ months of history? Contact us.

Rates by insurance carrier

Insurance Carrier
Aetna
Setting
Facility
Modifier
None
Typical Low
$128.82
Median
$218.78
Typical High
$398.11
Aetna
Setting
Professional
Modifier
None
Typical Low
$128.82
Median
$131.83
Typical High
$173.78
Anthem BCBS
Setting
Facility
Modifier
None
Typical Low
$169.82
Median
$169.82
Typical High
$831.76
Anthem BCBS
Setting
Professional
Modifier
None
Typical Low
$57.54
Median
$85.11
Typical High
$117.49
CareFirst
Setting
Professional
Modifier
None
Typical Low
$123.03
Median
$134.90
Typical High
$158.49
Cigna
Setting
Facility
Modifier
None
Typical Low
$173.78
Median
$323.59
Typical High
$501.19
Cigna
Setting
Professional
Modifier
None
Typical Low
$72.44
Median
$102.33
Typical High
$288.40
Kaiser Permanente
Setting
Professional
Modifier
None
Typical Low
$162.18
Median
$186.21
Typical High
$239.88
Medcost
Setting
Facility
Modifier
None
Typical Low
$173.78
Median
$173.78
Typical High
$302.00
Medcost
Setting
Professional
Modifier
None
Typical Low
$50.12
Median
$128.82
Typical High
$162.18
Sentara
Setting
Facility
Modifier
None
Typical Low
$120.23
Median
$234.42
Typical High
$10,232.93
Sentara
Setting
Professional
Modifier
None
Typical Low
$120.23
Median
$213.80
Typical High
$7,413.10
United
Setting
Facility
Modifier
None
Typical Low
$204.17
Median
$204.17
Typical High
$204.17
United
Setting
Professional
Modifier
None
Typical Low
$53.70
Median
$83.18
Typical High
$186.21
2 more rates with less common billing modifiers

A modifier changes what was billed, for example a reduced or repeated service. Each of these modifiers carries under 10% of the published rates for this code. Modifier combinations, and modifiers with fewer than 30 rates for a carrier, are not listed.

Insurance Carrier
Aetna
Setting
Professional
Modifier
52 · Reduced service
Typical Low
$63.10
Median
$63.10
Typical High
$72.44
Aetna
Setting
Professional
Modifier
53 · Discontinued
Typical Low
$25.70
Median
$25.70
Typical High
$28.84

Where Virginia sits

The same service costs 3.5 times more in Alaska than in North Carolina. Every bar is a state, most expensive first. Touch or drag across it to read any state, then open that state for its carriers and full range.

Virginia· 38th of 51

$138

AK $380NC $110

Median negotiated rate in each state, from every insurer that publishes one. States where no insurer publishes a rate for this service are not shown.