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High-Resolution Tissue-Type Test, Single Marker

South Dakota rates for HCPCS 81381

This is a detailed genetic test that examines one specific immune-system marker gene at high resolution, most often used before a bone marrow, stem cell, or organ transplant to see how closely a donor's tissue type matches the recipient's. Fine-grained matching on these markers helps predict how well a transplant will be tolerated. The test is run on a blood sample.

Rates data updated October 2026.

How much does High-Resolution Tissue-Type Test, Single Marker cost?

$191

Typical negotiated rate. In South Dakota, October 2026.

Insurers have agreed to pay about $191 for this service. The price depends on where it is billed: about $195 from a physician practice, and about $191 from a hospital or other facility.

These are rates insurers have negotiated with providers, not the amount a patient is billed. What you owe depends on your plan's deductible and coinsurance. Based on rates published by 6 insurance carriers under federal price transparency rules.

Prices by location type

Billed byTypicalRange
Physician practiceA doctor's office, clinic or independent provider$195$129 to $324
FacilityA hospital or hospital-owned outpatient department$191$191 to $324

How much rates vary

Facilitymedian $191 · 10th to 90th $151 to $324Professionalmedian $195 · 10th to 90th $71 to $407
$100$200$500facility $191professional $195

Distribution of negotiated rates across all payers (price axis is log-scale). Small sample; interpret with caution. Need provider-level prices or 24+ months of history? Contact us.

Rates by insurance carrier

Insurance Carrier
Aetna
Setting
Facility
Modifier
None
Typical Low
$120.23
Median
$120.23
Typical High
$194.98
Aetna
Setting
Professional
Modifier
None
Typical Low
$114.82
Median
$114.82
Typical High
$158.49
Cigna
Setting
Facility
Modifier
None
Typical Low
$323.59
Median
$323.59
Typical High
$323.59
Cigna
Setting
Professional
Modifier
None
Typical Low
$194.98
Median
$323.59
Typical High
$407.38
Medica
Setting
Facility
Modifier
None
Typical Low
$162.18
Median
$190.55
Typical High
$190.55
Medica
Setting
Professional
Modifier
None
Typical Low
$66.07
Median
$151.36
Typical High
$309.03
Sanford Health Plan
Setting
Professional
Modifier
None
Typical Low
$245.47
Median
$398.11
Typical High
$467.74
United
Setting
Professional
Modifier
None
Typical Low
$66.07
Median
$102.33
Typical High
$169.82
Wellmark
Setting
Professional
Modifier
None
Typical Low
$169.82
Median
$169.82
Typical High
$169.82

Where South Dakota sits

The same service costs 3.5 times more in Alaska than in North Carolina. Every bar is a state, most expensive first. Touch or drag across it to read any state, then open that state for its carriers and full range.

South Dakota· 12th of 51

$191

AK $380NC $110

Median negotiated rate in each state, from every insurer that publishes one. States where no insurer publishes a rate for this service are not shown.