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High-Resolution Tissue-Type Test, Single Marker

South Dakota rates for HCPCS 81381

This is a detailed genetic test that examines one specific immune-system marker gene at high resolution, most often used before a bone marrow, stem cell, or organ transplant to see how closely a donor's tissue type matches the recipient's. Fine-grained matching on these markers helps predict how well a transplant will be tolerated. The test is run on a blood sample.

Rates data updated July 2026.

How much does High-Resolution Tissue-Type Test, Single Marker cost?

$195

Typical negotiated rate. In South Dakota, July 2026.

Insurers have agreed to pay about $195 for this service. The price depends on where it is billed: about $170 from a physician practice, and about $324 from a hospital or other facility. The two figures are alternatives, not parts of one bill.

These are rates insurers have negotiated with providers, not the amount a patient is billed. What you owe depends on your plan's deductible and coinsurance. Based on rates published by 6 insurance carriers under federal price transparency rules.

Where it's billed changes the price

Billed byTypicalRange
Physician practiceA doctor's office, clinic or independent provider$170$115 to $339
FacilityA hospital or hospital-owned outpatient department$324$309 to $324

How much rates vary

Facilitymedian $324 · 10th to 90th $191 to $324Professionalmedian $170 · 10th to 90th $100 to $407
$100$200$500facility $324professional $170

Distribution of negotiated rates across all payers (price axis is log-scale). Each curve is scaled to its own total: facility and professional rates are different services, shown together to compare where they cluster. Need provider-level prices or 24+ months of history? Contact us.

Rates by insurance carrier

Insurance Carrier
Aetna
Setting
Facility
Modifier
Global
Typical Low
$120.23
Median
$194.98
Typical High
$194.98
Aetna
Setting
Professional
Modifier
Global
Typical Low
$100.00
Median
$114.82
Typical High
$158.49
Cigna
Setting
Facility
Modifier
Global
Typical Low
$323.59
Median
$323.59
Typical High
$323.59
Cigna
Setting
Professional
Modifier
Global
Typical Low
$245.47
Median
$323.59
Typical High
$407.38
Medica
Setting
Facility
Modifier
Global
Typical Low
$151.36
Median
$190.55
Typical High
$354.81
Medica
Setting
Professional
Modifier
Global
Typical Low
$66.07
Median
$70.79
Typical High
$851.14
Sanford Health Plan
Setting
Professional
Modifier
Global
Typical Low
$245.47
Median
$398.11
Typical High
$467.74
United
Setting
Professional
Modifier
Global
Typical Low
$66.07
Median
$102.33
Typical High
$194.98
Wellmark
Setting
Professional
Modifier
Global
Typical Low
$169.82
Median
$169.82
Typical High
$169.82

Where South Dakota sits

The same service costs 3.0 times more in Alaska than in Washington, DC. Every bar is a state, most expensive first. Touch or drag across it to read any state, then open that state for its carriers and full range.

South Dakota· 13th of 51

$195

AK $380DC $129

Median negotiated rate in each state, from every insurer that publishes one. States where no insurer publishes a rate for this service are not shown.