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High-Resolution Tissue-Type Test, Single Marker

South Carolina rates for HCPCS 81381

This is a detailed genetic test that examines one specific immune-system marker gene at high resolution, most often used before a bone marrow, stem cell, or organ transplant to see how closely a donor's tissue type matches the recipient's. Fine-grained matching on these markers helps predict how well a transplant will be tolerated. The test is run on a blood sample.

Rates data updated October 2026.

How much does High-Resolution Tissue-Type Test, Single Marker cost?

$132

Typical negotiated rate. In South Carolina, October 2026.

Insurers have agreed to pay about $132 for this service. The price depends on where it is billed: about $129 from a physician practice, and about $355 from a hospital or other facility.

These are rates insurers have negotiated with providers, not the amount a patient is billed. What you owe depends on your plan's deductible and coinsurance. Based on rates published by 5 insurance carriers under federal price transparency rules.

Prices by location type

Billed byTypicalRange
Physician practiceA doctor's office, clinic or independent provider$129$89.13 to $170
FacilityA hospital or hospital-owned outpatient department$355$178 to $776

How much rates vary

Facilitymedian $355 · 10th to 90th $132 to $1,047Professionalmedian $129 · 10th to 90th $72 to $182
$100$200$500$1Kfacility $355professional $129

Distribution of negotiated rates across all payers (price axis is log-scale). Small sample; interpret with caution. Need provider-level prices or 24+ months of history? Contact us.

Rates by insurance carrier

Insurance Carrier
Aetna
Setting
Facility
Modifier
None
Typical Low
$131.83
Median
$131.83
Typical High
$131.83
Aetna
Setting
Professional
Modifier
None
Typical Low
$131.83
Median
$131.83
Typical High
$162.18
BCBS South Carolina
Setting
Facility
Modifier
None
Typical Low
$912.01
Median
$912.01
Typical High
$933.25
BCBS South Carolina
Setting
Professional
Modifier
None
Typical Low
$89.13
Median
$162.18
Typical High
$177.83
Cigna
Setting
Facility
Modifier
None
Typical Low
$323.59
Median
$426.58
Typical High
$1,047.13
Cigna
Setting
Professional
Modifier
None
Typical Low
$60.26
Median
$79.43
Typical High
$177.83
Medcost
Setting
Facility
Modifier
None
Typical Low
$123.03
Median
$144.54
Typical High
$489.78
Medcost
Setting
Professional
Modifier
None
Typical Low
$128.82
Median
$128.82
Typical High
$218.78
United
Setting
Facility
Modifier
None
Typical Low
$151.36
Median
$151.36
Typical High
$204.17
United
Setting
Professional
Modifier
None
Typical Low
$64.57
Median
$85.11
Typical High
$154.88
3 more rates with less common billing modifiers

A modifier changes what was billed, for example a reduced or repeated service. Each of these modifiers carries under 10% of the published rates for this code. Modifier combinations, and modifiers with fewer than 30 rates for a carrier, are not listed.

Insurance Carrier
Aetna
Setting
Professional
Modifier
52 · Reduced service
Typical Low
$66.07
Median
$66.07
Typical High
$67.61
Aetna
Setting
Professional
Modifier
53 · Discontinued
Typical Low
$26.30
Median
$26.30
Typical High
$26.92
Medcost
Setting
Professional
Modifier
51 · Multiple procedures
Typical Low
$64.57
Median
$64.57
Typical High
$128.82

Where South Carolina sits

The same service costs 3.5 times more in Alaska than in North Carolina. Every bar is a state, most expensive first. Touch or drag across it to read any state, then open that state for its carriers and full range.

South Carolina· 42nd of 51

$132

AK $380NC $110

Median negotiated rate in each state, from every insurer that publishes one. States where no insurer publishes a rate for this service are not shown.