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High-Resolution Tissue-Type Test, Single Marker

Pennsylvania rates for HCPCS 81381

This is a detailed genetic test that examines one specific immune-system marker gene at high resolution, most often used before a bone marrow, stem cell, or organ transplant to see how closely a donor's tissue type matches the recipient's. Fine-grained matching on these markers helps predict how well a transplant will be tolerated. The test is run on a blood sample.

Rates data updated July 2026.

Facilitymedian $282 · 10th–90th $145$7940%10%10th90th$282Professionalmedian $138 · 10th–90th $71$3800%20%10th90th$138$100.0$500.0$2.0K$10.0K$50.0K

Distribution of negotiated rates across all payers (price axis is log-scale). Facility and professional rates are different services and are charted separately. Need provider-level prices? Contact us.

Insurance Carrier
Aetna
Setting
Facility
Modifier
Global
Typical Low
$138.04
Median
$263.03
Typical High
$794.33
Aetna
Setting
Professional
Modifier
Global
Typical Low
$77.62
Median
$138.04
Typical High
$602.56
Capital Blue Cross
Setting
Facility
Modifier
Global
Typical Low
$467.74
Median
$630.96
Typical High
$8,511.38
Capital Blue Cross
Setting
Professional
Modifier
Global
Typical Low
$131.83
Median
$131.83
Typical High
$131.83
Cigna
Setting
Facility
Modifier
Global
Typical Low
$165.96
Median
$275.42
Typical High
$575.44
Cigna
Setting
Professional
Modifier
Global
Typical Low
$60.26
Median
$154.88
Typical High
$380.19
Emblem Health
Setting
Professional
Modifier
Global
Typical Low
$120.23
Median
$120.23
Typical High
$223.87
Geisinger
Setting
Facility
Modifier
Global
Typical Low
$169.82
Median
$169.82
Typical High
$169.82
Geisinger
Setting
Professional
Modifier
Global
Typical Low
$125.89
Median
$263.03
Typical High
$426.58
Highmark BCBS
Setting
Facility
Modifier
Global
Typical Low
$257.04
Median
$436.52
Typical High
$794.33
Independence Blue Cross
Setting
Professional
Modifier
Global
Typical Low
$169.82
Median
$169.82
Typical High
$169.82
Martin's Point
Setting
Facility
Modifier
Global
Typical Low
$138.04
Median
$263.03
Typical High
$630.96
Martin's Point
Setting
Professional
Modifier
Global
Typical Low
$77.62
Median
$144.54
Typical High
$602.56
UPMC Health Plan
Setting
Facility
Modifier
Global
Typical Low
$218.78
Median
$467.74
Typical High
$977.24
UPMC Health Plan
Setting
Professional
Modifier
Global
Typical Low
$144.54
Median
$169.82
Typical High
$173.78
United
Setting
Facility
Modifier
Global
Typical Low
$151.36
Median
$169.82
Typical High
$204.17
United
Setting
Professional
Modifier
Global
Typical Low
$70.79
Median
$102.33
Typical High
$239.88