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High-Resolution Tissue-Type Test, Single Marker

Ohio rates for HCPCS 81381

This is a detailed genetic test that examines one specific immune-system marker gene at high resolution, most often used before a bone marrow, stem cell, or organ transplant to see how closely a donor's tissue type matches the recipient's. Fine-grained matching on these markers helps predict how well a transplant will be tolerated. The test is run on a blood sample.

Rates data updated October 2026.

How much does High-Resolution Tissue-Type Test, Single Marker cost?

$135

Typical negotiated rate. In Ohio, October 2026.

Insurers have agreed to pay about $135 for this service. The price depends on where it is billed: about $89.13 from a physician practice, and about $224 from a hospital or other facility.

These are rates insurers have negotiated with providers, not the amount a patient is billed. What you owe depends on your plan's deductible and coinsurance. Based on rates published by 8 insurance carriers under federal price transparency rules.

Prices by location type

Billed byTypicalRange
Physician practiceA doctor's office, clinic or independent provider$89.13$67.61 to $170
FacilityA hospital or hospital-owned outpatient department$224$178 to $295

How much rates vary

Facilitymedian $224 · 10th to 90th $155 to $468Professionalmedian $89 · 10th to 90th $68 to $339
$100$200$500$1Kfacility $224professional $89

Distribution of negotiated rates across all payers (price axis is log-scale). Need provider-level prices or 24+ months of history? Contact us.

Rates by insurance carrier

Insurance Carrier
Aetna
Setting
Facility
Modifier
None
Typical Low
$169.82
Median
$363.08
Typical High
$537.03
Aetna
Setting
Facility
Modifier
52 · Reduced service
Typical Low
$67.61
Median
$123.03
Typical High
$204.17
Aetna
Setting
Facility
Modifier
53 · Discontinued
Typical Low
$26.92
Median
$48.98
Typical High
$81.28
Aetna
Setting
Professional
Modifier
None
Typical Low
$134.90
Median
$144.54
Typical High
$537.03
Aetna
Setting
Professional
Modifier
52 · Reduced service
Typical Low
$67.61
Median
$67.61
Typical High
$204.17
Aetna
Setting
Professional
Modifier
53 · Discontinued
Typical Low
$26.92
Median
$26.92
Typical High
$81.28
Anthem BCBS
Setting
Facility
Modifier
None
Typical Low
$138.04
Median
$194.98
Typical High
$316.23
Anthem BCBS
Setting
Professional
Modifier
None
Typical Low
$67.61
Median
$67.61
Typical High
$239.88
CareSource
Setting
Professional
Modifier
None
Typical Low
$169.82
Median
$169.82
Typical High
$229.09
Cigna
Setting
Facility
Modifier
None
Typical Low
$165.96
Median
$204.17
Typical High
$691.83
Cigna
Setting
Professional
Modifier
None
Typical Low
$77.62
Median
$77.62
Typical High
$302.00
Medical Mutual of Ohio
Setting
Facility
Modifier
None
Typical Low
$181.97
Median
$213.80
Typical High
$691.83
Medical Mutual of Ohio
Setting
Professional
Modifier
None
Typical Low
$77.62
Median
$77.62
Typical High
$302.00
Molina
Setting
Professional
Modifier
None
Typical Low
$117.49
Median
$151.36
Typical High
$208.93
SummaCare
Setting
Professional
Modifier
None
Typical Low
$144.54
Median
$208.93
Typical High
$269.15
United
Setting
Facility
Modifier
None
Typical Low
$61.66
Median
$151.36
Typical High
$257.04
United
Setting
Professional
Modifier
None
Typical Low
$70.79
Median
$102.33
Typical High
$245.47

Where Ohio sits

The same service costs 3.5 times more in Alaska than in North Carolina. Every bar is a state, most expensive first. Touch or drag across it to read any state, then open that state for its carriers and full range.

Ohio· 40th of 51

$135

AK $380NC $110

Median negotiated rate in each state, from every insurer that publishes one. States where no insurer publishes a rate for this service are not shown.