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High-Resolution Tissue-Type Test, Single Marker

Missouri rates for HCPCS 81381

This is a detailed genetic test that examines one specific immune-system marker gene at high resolution, most often used before a bone marrow, stem cell, or organ transplant to see how closely a donor's tissue type matches the recipient's. Fine-grained matching on these markers helps predict how well a transplant will be tolerated. The test is run on a blood sample.

Rates data updated October 2026.

How much does High-Resolution Tissue-Type Test, Single Marker cost?

$162

Typical negotiated rate. In Missouri, October 2026.

Insurers have agreed to pay about $162 for this service. The price depends on where it is billed: about $145 from a physician practice, and about $295 from a hospital or other facility.

These are rates insurers have negotiated with providers, not the amount a patient is billed. What you owe depends on your plan's deductible and coinsurance. Based on rates published by 6 insurance carriers under federal price transparency rules.

Prices by location type

Billed byTypicalRange
Physician practiceA doctor's office, clinic or independent provider$145$87.10 to $257
FacilityA hospital or hospital-owned outpatient department$295$170 to $525

How much rates vary

Facilitymedian $295 · 10th to 90th $148 to $813Professionalmedian $145 · 10th to 90th $83 to $447
$100$200$500$1Kfacility $295professional $145

Distribution of negotiated rates across all payers (price axis is log-scale). Need provider-level prices or 24+ months of history? Contact us.

Rates by insurance carrier

Insurance Carrier
Aetna
Setting
Facility
Modifier
None
Typical Low
$144.54
Median
$165.96
Typical High
$316.23
Aetna
Setting
Professional
Modifier
None
Typical Low
$144.54
Median
$144.54
Typical High
$181.97
Anthem BCBS
Setting
Facility
Modifier
None
Typical Low
$169.82
Median
$169.82
Typical High
$776.25
Anthem BCBS
Setting
Professional
Modifier
None
Typical Low
$87.10
Median
$154.88
Typical High
$309.03
BCBS Kansas City
Setting
Professional
Modifier
None
Typical Low
$120.23
Median
$128.82
Typical High
$323.59
Cigna
Setting
Facility
Modifier
None
Typical Low
$138.04
Median
$380.19
Typical High
$537.03
Cigna
Setting
Professional
Modifier
None
Typical Low
$77.62
Median
$162.18
Typical High
$245.47
Medica
Setting
Facility
Modifier
None
Typical Low
$151.36
Median
$295.12
Typical High
$812.83
Medica
Setting
Professional
Modifier
None
Typical Low
$77.62
Median
$169.82
Typical High
$851.14
United
Setting
Facility
Modifier
None
Typical Low
$151.36
Median
$151.36
Typical High
$151.36
United
Setting
Professional
Modifier
None
Typical Low
$70.79
Median
$102.33
Typical High
$223.87
2 more rates with less common billing modifiers

A modifier changes what was billed, for example a reduced or repeated service. Each of these modifiers carries under 10% of the published rates for this code. Modifier combinations, and modifiers with fewer than 30 rates for a carrier, are not listed.

Insurance Carrier
Aetna
Setting
Professional
Modifier
52 · Reduced service
Typical Low
$72.44
Median
$72.44
Typical High
$97.72
Aetna
Setting
Professional
Modifier
53 · Discontinued
Typical Low
$28.84
Median
$29.51
Typical High
$38.90

Where Missouri sits

The same service costs 3.5 times more in Alaska than in North Carolina. Every bar is a state, most expensive first. Touch or drag across it to read any state, then open that state for its carriers and full range.

Missouri· 26th of 51

$162

AK $380NC $110

Median negotiated rate in each state, from every insurer that publishes one. States where no insurer publishes a rate for this service are not shown.