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High-Resolution Tissue-Type Test, Single Marker

Minnesota rates for HCPCS 81381

This is a detailed genetic test that examines one specific immune-system marker gene at high resolution, most often used before a bone marrow, stem cell, or organ transplant to see how closely a donor's tissue type matches the recipient's. Fine-grained matching on these markers helps predict how well a transplant will be tolerated. The test is run on a blood sample.

Rates data updated October 2026.

How much does High-Resolution Tissue-Type Test, Single Marker cost?

$170

Typical negotiated rate. In Minnesota, October 2026.

Insurers have agreed to pay about $170 for this service. The price depends on where it is billed: about $170 from a physician practice, and about $170 from a hospital or other facility.

These are rates insurers have negotiated with providers, not the amount a patient is billed. What you owe depends on your plan's deductible and coinsurance. Based on rates published by 6 insurance carriers under federal price transparency rules.

Prices by location type

Billed byTypicalRange
Physician practiceA doctor's office, clinic or independent provider$170$141 to $204
FacilityA hospital or hospital-owned outpatient department$170$158 to $407

How much rates vary

Facilitymedian $170 · 10th to 90th $158 to $661Professionalmedian $170 · 10th to 90th $87 to $339
$100$200$500$1Kfacility $170professional $170

Distribution of negotiated rates across all payers (price axis is log-scale). Need provider-level prices or 24+ months of history? Contact us.

Rates by insurance carrier

Insurance Carrier
Aetna
Setting
Facility
Modifier
None
Typical Low
$158.49
Median
$158.49
Typical High
$158.49
Aetna
Setting
Professional
Modifier
None
Typical Low
$158.49
Median
$158.49
Typical High
$204.17
BCBS Minnesota
Setting
Facility
Modifier
None
Typical Low
$162.18
Median
$169.82
Typical High
$446.68
BCBS Minnesota
Setting
Professional
Modifier
None
Typical Low
$134.90
Median
$151.36
Typical High
$169.82
Cigna
Setting
Facility
Modifier
None
Typical Low
$338.84
Median
$549.54
Typical High
$1,584.89
Cigna
Setting
Professional
Modifier
None
Typical Low
$199.53
Median
$223.87
Typical High
$331.13
Health Partners
Setting
Facility
Modifier
None
Typical Low
$323.59
Median
$524.81
Typical High
$1,258.93
Health Partners
Setting
Professional
Modifier
None
Typical Low
$194.98
Median
$194.98
Typical High
$302.00
Medica
Setting
Facility
Modifier
None
Typical Low
$194.98
Median
$269.15
Typical High
$407.38
Medica
Setting
Professional
Modifier
None
Typical Low
$66.07
Median
$169.82
Typical High
$851.14
United
Setting
Facility
Modifier
None
Typical Low
$169.82
Median
$169.82
Typical High
$204.17
United
Setting
Professional
Modifier
None
Typical Low
$66.07
Median
$128.82
Typical High
$398.11
4 more rates with less common billing modifiers

A modifier changes what was billed, for example a reduced or repeated service. Each of these modifiers carries under 10% of the published rates for this code. Modifier combinations, and modifiers with fewer than 30 rates for a carrier, are not listed.

Insurance Carrier
Aetna
Setting
Facility
Modifier
52 · Reduced service
Typical Low
$79.43
Median
$79.43
Typical High
$79.43
Aetna
Setting
Facility
Modifier
53 · Discontinued
Typical Low
$31.62
Median
$31.62
Typical High
$31.62
Aetna
Setting
Professional
Modifier
52 · Reduced service
Typical Low
$79.43
Median
$79.43
Typical High
$81.28
Aetna
Setting
Professional
Modifier
53 · Discontinued
Typical Low
$31.62
Median
$31.62
Typical High
$32.36

Where Minnesota sits

The same service costs 3.5 times more in Alaska than in North Carolina. Every bar is a state, most expensive first. Touch or drag across it to read any state, then open that state for its carriers and full range.

Minnesota· 24th of 51

$170

AK $380NC $110

Median negotiated rate in each state, from every insurer that publishes one. States where no insurer publishes a rate for this service are not shown.