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High-Resolution Tissue-Type Test, Single Marker

Michigan rates for HCPCS 81381

This is a detailed genetic test that examines one specific immune-system marker gene at high resolution, most often used before a bone marrow, stem cell, or organ transplant to see how closely a donor's tissue type matches the recipient's. Fine-grained matching on these markers helps predict how well a transplant will be tolerated. The test is run on a blood sample.

Rates data updated October 2026.

How much does High-Resolution Tissue-Type Test, Single Marker cost?

$141

Typical negotiated rate. In Michigan, October 2026.

Insurers have agreed to pay about $141 for this service. The price depends on where it is billed: about $129 from a physician practice, and about $162 from a hospital or other facility.

These are rates insurers have negotiated with providers, not the amount a patient is billed. What you owe depends on your plan's deductible and coinsurance. Based on rates published by 7 insurance carriers under federal price transparency rules.

Prices by location type

Billed byTypicalRange
Physician practiceA doctor's office, clinic or independent provider$129$120 to $162
FacilityA hospital or hospital-owned outpatient department$162$162 to $214

How much rates vary

Facilitymedian $162 · 10th to 90th $129 to $309Professionalmedian $129 · 10th to 90th $78 to $174
$10$20$50$100$200$500facility $162professional $129

Distribution of negotiated rates across all payers (price axis is log-scale). Need provider-level prices or 24+ months of history? Contact us.

Rates by insurance carrier

Insurance Carrier
Aetna
Setting
Facility
Modifier
None
Typical Low
$162.18
Median
$162.18
Typical High
$251.19
Aetna
Setting
Facility
Modifier
52 · Reduced service
Typical Low
$81.28
Median
$81.28
Typical High
$125.89
Aetna
Setting
Facility
Modifier
53 · Discontinued
Typical Low
$32.36
Median
$32.36
Typical High
$50.12
Aetna
Setting
Professional
Modifier
None
Typical Low
$154.88
Median
$165.96
Typical High
$199.53
Aetna
Setting
Professional
Modifier
52 · Reduced service
Typical Low
$77.62
Median
$83.18
Typical High
$85.11
Aetna
Setting
Professional
Modifier
53 · Discontinued
Typical Low
$30.90
Median
$33.11
Typical High
$34.67
BCBS Michigan
Setting
Facility
Modifier
None
Typical Low
$128.82
Median
$181.97
Typical High
$316.23
BCBS Michigan
Setting
Professional
Modifier
None
Typical Low
$120.23
Median
$128.82
Typical High
$128.82
CareSource
Setting
Professional
Modifier
None
Typical Low
$169.82
Median
$186.21
Typical High
$229.09
Cigna
Setting
Professional
Modifier
None
Typical Low
$58.88
Median
$77.62
Typical High
$234.42
Health Alliance Plan
Setting
Facility
Modifier
None
Typical Low
$162.18
Median
$162.18
Typical High
$331.13
Health Alliance Plan
Setting
Facility
Modifier
52 · Reduced service
Typical Low
$81.28
Median
$81.28
Typical High
$125.89
Health Alliance Plan
Setting
Facility
Modifier
53 · Discontinued
Typical Low
$32.36
Median
$32.36
Typical High
$50.12
Health Alliance Plan
Setting
Professional
Modifier
None
Typical Low
$120.23
Median
$158.49
Typical High
$190.55
Health Alliance Plan
Setting
Professional
Modifier
52 · Reduced service
Typical Low
$81.28
Median
$81.28
Typical High
$81.28
Health Alliance Plan
Setting
Professional
Modifier
53 · Discontinued
Typical Low
$32.36
Median
$32.36
Typical High
$32.36
Priority Health
Setting
Professional
Modifier
None
Typical Low
$58.88
Median
$77.62
Typical High
$234.42
United
Setting
Facility
Modifier
None
Typical Low
$102.33
Median
$151.36
Typical High
$204.17
United
Setting
Professional
Modifier
None
Typical Low
$53.70
Median
$77.62
Typical High
$128.82

Where Michigan sits

The same service costs 3.5 times more in Alaska than in North Carolina. Every bar is a state, most expensive first. Touch or drag across it to read any state, then open that state for its carriers and full range.

Michigan· 33rd of 51

$141

AK $380NC $110

Median negotiated rate in each state, from every insurer that publishes one. States where no insurer publishes a rate for this service are not shown.