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High-Resolution Tissue-Type Test, Single Marker

Maryland rates for HCPCS 81381

This is a detailed genetic test that examines one specific immune-system marker gene at high resolution, most often used before a bone marrow, stem cell, or organ transplant to see how closely a donor's tissue type matches the recipient's. Fine-grained matching on these markers helps predict how well a transplant will be tolerated. The test is run on a blood sample.

Rates data updated October 2026.

How much does High-Resolution Tissue-Type Test, Single Marker cost?

$129

Typical negotiated rate. In Maryland, October 2026.

Insurers have agreed to pay about $129 for this service. Most negotiated rates run $112 to $135.

These are rates insurers have negotiated with providers, not the amount a patient is billed. What you owe depends on your plan's deductible and coinsurance. Based on rates published by 6 insurance carriers under federal price transparency rules.

How much rates vary

Professionalmedian $129 · 10th to 90th $76 to $170
$100$200professional $129

Distribution of negotiated rates across all payers (price axis is log-scale). Need provider-level prices or 24+ months of history? Contact us.

Rates by insurance carrier

Insurance Carrier
Aetna
Setting
Professional
Modifier
None
Typical Low
$125.89
Median
$128.82
Typical High
$154.88
CareFirst
Setting
Professional
Modifier
None
Typical Low
$123.03
Median
$134.90
Typical High
$144.54
Cigna
Setting
Professional
Modifier
None
Typical Low
$72.44
Median
$120.23
Typical High
$489.78
Kaiser Permanente
Setting
Professional
Modifier
None
Typical Low
$169.82
Median
$204.17
Typical High
$257.04
United
Setting
Professional
Modifier
None
Typical Low
$53.70
Median
$85.11
Typical High
$141.25
Wellpoint
Setting
Professional
Modifier
None
Typical Low
$134.90
Median
$134.90
Typical High
$134.90
2 more rates with less common billing modifiers

A modifier changes what was billed, for example a reduced or repeated service. Each of these modifiers carries under 10% of the published rates for this code. Modifier combinations, and modifiers with fewer than 30 rates for a carrier, are not listed.

Insurance Carrier
Aetna
Setting
Professional
Modifier
52 · Reduced service
Typical Low
$63.10
Median
$63.10
Typical High
$72.44
Aetna
Setting
Professional
Modifier
53 · Discontinued
Typical Low
$25.12
Median
$25.70
Typical High
$28.84

Where Maryland sits

The same service costs 3.5 times more in Alaska than in North Carolina. Every bar is a state, most expensive first. Touch or drag across it to read any state, then open that state for its carriers and full range.

Maryland· 45th of 51

$129

AK $380NC $110

Median negotiated rate in each state, from every insurer that publishes one. States where no insurer publishes a rate for this service are not shown.