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High-Resolution Tissue-Type Test, Single Marker

Massachusetts rates for HCPCS 81381

This is a detailed genetic test that examines one specific immune-system marker gene at high resolution, most often used before a bone marrow, stem cell, or organ transplant to see how closely a donor's tissue type matches the recipient's. Fine-grained matching on these markers helps predict how well a transplant will be tolerated. The test is run on a blood sample.

Rates data updated July 2026.

How much does High-Resolution Tissue-Type Test, Single Marker cost?

$170

Typical negotiated rate. In Massachusetts, July 2026.

Insurers have agreed to pay about $170 for this service. The price depends on where it is billed: about $170 from a physician practice, and about $339 from a hospital or other facility. The two figures are alternatives, not parts of one bill.

These are rates insurers have negotiated with providers, not the amount a patient is billed. What you owe depends on your plan's deductible and coinsurance. Based on rates published by 9 insurance carriers under federal price transparency rules.

Where it's billed changes the price

Billed byTypicalRange
Physician practiceA doctor's office, clinic or independent provider$170$162 to $191
FacilityA hospital or hospital-owned outpatient department$339$234 to $479

How much rates vary

Facilitymedian $339 · 10th to 90th $126 to $550Professionalmedian $170 · 10th to 90th $89 to $380
$100.0$1.0K$10.0Kfacility $339professional $170

Distribution of negotiated rates across all payers (price axis is log-scale). Each curve is scaled to its own total: facility and professional rates are different services, shown together to compare where they cluster. Need provider-level prices or 24+ months of history? Contact us.

Rates by insurance carrier

Insurance Carrier
Aetna
Setting
Facility
Modifier
Global
Typical Low
$89.13
Median
$316.23
Typical High
$724.44
Aetna
Setting
Professional
Modifier
Global
Typical Low
$70.79
Median
$162.18
Typical High
$512.86
AllWays Health Partners
Setting
Facility
Modifier
Global
Typical Low
$125.89
Median
$194.98
Typical High
$537.03
AllWays Health Partners
Setting
Professional
Modifier
Global
Typical Low
$77.62
Median
$169.82
Typical High
$562.34
BCBS
Setting
Facility
Modifier
Global
Typical Low
$269.15
Median
$338.84
Typical High
$489.78
BCBS
Setting
Professional
Modifier
Global
Typical Low
$158.49
Median
$158.49
Typical High
$158.49
Cigna
Setting
Facility
Modifier
Global
Typical Low
$109.65
Median
$190.55
Typical High
$331.13
Cigna
Setting
Professional
Modifier
Global
Typical Low
$85.11
Median
$177.83
Typical High
$446.68
Fallon Health
Setting
Facility
Modifier
Global
Typical Low
$83.18
Median
$3,630.78
Typical High
$9,772.37
Fallon Health
Setting
Professional
Modifier
Global
Typical Low
$128.82
Median
$245.47
Typical High
$288.40
Harvard Pilgrim
Setting
Professional
Modifier
Global
Typical Low
$169.82
Median
$169.82
Typical High
$295.12
Health New England
Setting
Facility
Modifier
Global
Typical Low
$123.03
Median
$181.97
Typical High
$912.01
Mass General Brigham
Setting
Facility
Modifier
Global
Typical Low
$125.89
Median
$194.98
Typical High
$537.03
Mass General Brigham
Setting
Professional
Modifier
Global
Typical Low
$77.62
Median
$169.82
Typical High
$562.34
United
Setting
Facility
Modifier
Global
Typical Low
$102.33
Median
$154.88
Typical High
$194.98
United
Setting
Professional
Modifier
Global
Typical Low
$77.62
Median
$169.82
Typical High
$371.54

Where Massachusetts sits

The same service costs 3.0 times more in Alaska than in Washington, DC. Every bar is a state, most expensive first. Pick one to see its carriers and full range.

Massachusetts $170 · 28th of 51
AK $380DC $129

Median negotiated rate in each state, from every insurer that publishes one. States where no insurer publishes a rate for this service are not shown.