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High-Resolution Tissue-Type Test, Single Marker

Indiana rates for HCPCS 81381

This is a detailed genetic test that examines one specific immune-system marker gene at high resolution, most often used before a bone marrow, stem cell, or organ transplant to see how closely a donor's tissue type matches the recipient's. Fine-grained matching on these markers helps predict how well a transplant will be tolerated. The test is run on a blood sample.

Rates data updated October 2026.

How much does High-Resolution Tissue-Type Test, Single Marker cost?

$138

Typical negotiated rate. In Indiana, October 2026.

Insurers have agreed to pay about $138 for this service. The price depends on where it is billed: about $105 from a physician practice, and about $170 from a hospital or other facility.

These are rates insurers have negotiated with providers, not the amount a patient is billed. What you owe depends on your plan's deductible and coinsurance. Based on rates published by 6 insurance carriers under federal price transparency rules.

Prices by location type

Billed byTypicalRange
Physician practiceA doctor's office, clinic or independent provider$105$67.61 to $170
FacilityA hospital or hospital-owned outpatient department$170$151 to $372

How much rates vary

Facilitymedian $170 · 10th to 90th $135 to $513Professionalmedian $105 · 10th to 90th $68 to $257
$100$200$500$1K$2Kfacility $170professional $105

Distribution of negotiated rates across all payers (price axis is log-scale). Need provider-level prices or 24+ months of history? Contact us.

Rates by insurance carrier

Insurance Carrier
Aetna
Setting
Facility
Modifier
None
Typical Low
$138.04
Median
$257.04
Typical High
$630.96
Aetna
Setting
Professional
Modifier
None
Typical Low
$128.82
Median
$138.04
Typical High
$257.04
Anthem BCBS
Setting
Facility
Modifier
None
Typical Low
$134.90
Median
$169.82
Typical High
$512.86
Anthem BCBS
Setting
Professional
Modifier
None
Typical Low
$67.61
Median
$67.61
Typical High
$257.04
CareSource
Setting
Professional
Modifier
None
Typical Low
$169.82
Median
$186.21
Typical High
$239.88
Cigna
Setting
Facility
Modifier
None
Typical Low
$109.65
Median
$169.82
Typical High
$478.63
Cigna
Setting
Professional
Modifier
None
Typical Low
$89.13
Median
$151.36
Typical High
$323.59
Physicians Health Plan of Northern Indiana
Setting
Facility
Modifier
None
Typical Low
$218.78
Median
$426.58
Typical High
$2,187.76
Physicians Health Plan of Northern Indiana
Setting
Professional
Modifier
None
Typical Low
$123.03
Median
$144.54
Typical High
$257.04
United
Setting
Professional
Modifier
None
Typical Low
$70.79
Median
$102.33
Typical High
$204.17
2 more rates with less common billing modifiers

A modifier changes what was billed, for example a reduced or repeated service. Each of these modifiers carries under 10% of the published rates for this code. Modifier combinations, and modifiers with fewer than 30 rates for a carrier, are not listed.

Insurance Carrier
Aetna
Setting
Professional
Modifier
52 · Reduced service
Typical Low
$63.10
Median
$69.18
Typical High
$128.82
Aetna
Setting
Professional
Modifier
53 · Discontinued
Typical Low
$25.70
Median
$27.54
Typical High
$51.29

Where Indiana sits

The same service costs 3.5 times more in Alaska than in North Carolina. Every bar is a state, most expensive first. Touch or drag across it to read any state, then open that state for its carriers and full range.

Indiana· 36th of 51

$138

AK $380NC $110

Median negotiated rate in each state, from every insurer that publishes one. States where no insurer publishes a rate for this service are not shown.