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High-Resolution Tissue-Type Test, Single Marker

Illinois rates for HCPCS 81381

This is a detailed genetic test that examines one specific immune-system marker gene at high resolution, most often used before a bone marrow, stem cell, or organ transplant to see how closely a donor's tissue type matches the recipient's. Fine-grained matching on these markers helps predict how well a transplant will be tolerated. The test is run on a blood sample.

Rates data updated July 2026.

How much does High-Resolution Tissue-Type Test, Single Marker cost?

$138

Typical negotiated rate. In Illinois, July 2026.

Insurers have agreed to pay about $138 for this service. The price depends on where it is billed: about $135 from a physician practice, and about $257 from a hospital or other facility. The two figures are alternatives, not parts of one bill.

These are rates insurers have negotiated with providers, not the amount a patient is billed. What you owe depends on your plan's deductible and coinsurance. Based on rates published by 5 insurance carriers under federal price transparency rules.

Where it's billed changes the price

Billed byTypicalRange
Physician practiceA doctor's office, clinic or independent provider$135$100 to $162
FacilityA hospital or hospital-owned outpatient department$257$174 to $339

How much rates vary

Facilitymedian $257 · 10th to 90th $138 to $468Professionalmedian $135 · 10th to 90th $3 to $245
$5$20$100$500$2Kfacility $257professional $135

Distribution of negotiated rates across all payers (price axis is log-scale). Each curve is scaled to its own total: facility and professional rates are different services, shown together to compare where they cluster. Need provider-level prices or 24+ months of history? Contact us.

Rates by insurance carrier

Insurance Carrier
Aetna
Setting
Facility
Modifier
Global
Typical Low
$138.04
Median
$257.04
Typical High
$346.74
Aetna
Setting
Professional
Modifier
Global
Typical Low
$104.71
Median
$144.54
Typical High
$316.23
BCBS
Setting
Facility
Modifier
Global
Typical Low
$208.93
Median
$602.56
Typical High
$2,137.96
BCBS
Setting
Professional
Modifier
Global
Typical Low
$3.47
Median
$117.49
Typical High
$131.83
Cigna
Setting
Facility
Modifier
Global
Typical Low
$199.53
Median
$363.08
Typical High
$776.25
Cigna
Setting
Professional
Modifier
Global
Typical Low
$77.62
Median
$199.53
Typical High
$288.40
Hally Health
Setting
Professional
Modifier
Global
Typical Low
$177.83
Median
$295.12
Typical High
$537.03
Hally Health
Setting
Facility
Modifier
Global
Typical Low
$100.00
Median
$100.00
Typical High
$100.00
Hally Health
Setting
Professional
Modifier
Global
Typical Low
$218.78
Median
$218.78
Typical High
$218.78
United
Setting
Facility
Modifier
Global
Typical Low
$154.88
Median
$169.82
Typical High
$338.84
United
Setting
Professional
Modifier
Global
Typical Low
$70.79
Median
$77.62
Typical High
$169.82

Where Illinois sits

The same service costs 3.0 times more in Alaska than in Washington, DC. Every bar is a state, most expensive first. Touch or drag across it to read any state, then open that state for its carriers and full range.

Illinois· 45th of 51

$138

AK $380DC $129

Median negotiated rate in each state, from every insurer that publishes one. States where no insurer publishes a rate for this service are not shown.