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High-Resolution Tissue-Type Test, Single Marker

Iowa rates for HCPCS 81381

This is a detailed genetic test that examines one specific immune-system marker gene at high resolution, most often used before a bone marrow, stem cell, or organ transplant to see how closely a donor's tissue type matches the recipient's. Fine-grained matching on these markers helps predict how well a transplant will be tolerated. The test is run on a blood sample.

Rates data updated October 2026.

How much does High-Resolution Tissue-Type Test, Single Marker cost?

$182

Typical negotiated rate. In Iowa, October 2026.

Insurers have agreed to pay about $182 for this service. The price depends on where it is billed: about $170 from a physician practice, and about $263 from a hospital or other facility.

These are rates insurers have negotiated with providers, not the amount a patient is billed. What you owe depends on your plan's deductible and coinsurance. Based on rates published by 8 insurance carriers under federal price transparency rules.

Prices by location type

Billed byTypicalRange
Physician practiceA doctor's office, clinic or independent provider$170$102 to $302
FacilityA hospital or hospital-owned outpatient department$263$191 to $347

How much rates vary

Facilitymedian $263 · 10th to 90th $170 to $437Professionalmedian $170 · 10th to 90th $102 to $479
$100$200$500facility $263professional $170

Distribution of negotiated rates across all payers (price axis is log-scale). Need provider-level prices or 24+ months of history? Contact us.

Rates by insurance carrier

Insurance Carrier
Aetna
Setting
Facility
Modifier
None
Typical Low
$131.83
Median
$263.03
Typical High
$478.63
Aetna
Setting
Professional
Modifier
None
Typical Low
$114.82
Median
$131.83
Typical High
$204.17
Cigna
Setting
Professional
Modifier
None
Typical Low
$208.93
Median
$323.59
Typical High
$407.38
Hally Health
Setting
Professional
Modifier
None
Typical Low
$169.82
Median
$213.80
Typical High
$363.08
Medica
Setting
Facility
Modifier
None
Typical Low
$169.82
Median
$218.78
Typical High
$389.05
Medica
Setting
Professional
Modifier
None
Typical Low
$102.33
Median
$204.17
Typical High
$851.14
Midlands
Setting
Professional
Modifier
None
Typical Low
$208.93
Median
$208.93
Typical High
$223.87
Oscar Health
Setting
Professional
Modifier
None
Typical Low
$169.82
Median
$181.97
Typical High
$363.08
United
Setting
Facility
Modifier
None
Typical Low
$169.82
Median
$169.82
Typical High
$436.52
United
Setting
Professional
Modifier
None
Typical Low
$77.62
Median
$102.33
Typical High
$316.23
Wellmark
Setting
Professional
Modifier
None
Typical Low
$169.82
Median
$169.82
Typical High
$169.82
2 more rates with less common billing modifiers

A modifier changes what was billed, for example a reduced or repeated service. Each of these modifiers carries under 10% of the published rates for this code. Modifier combinations, and modifiers with fewer than 30 rates for a carrier, are not listed.

Insurance Carrier
Aetna
Setting
Professional
Modifier
52 · Reduced service
Typical Low
$66.07
Median
$66.07
Typical High
$102.33
Aetna
Setting
Professional
Modifier
53 · Discontinued
Typical Low
$26.30
Median
$26.30
Typical High
$40.74

Where Iowa sits

The same service costs 3.5 times more in Alaska than in North Carolina. Every bar is a state, most expensive first. Touch or drag across it to read any state, then open that state for its carriers and full range.

Iowa· 16th of 51

$182

AK $380NC $110

Median negotiated rate in each state, from every insurer that publishes one. States where no insurer publishes a rate for this service are not shown.