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High-Resolution Tissue-Type Test, Single Marker

Florida rates for HCPCS 81381

This is a detailed genetic test that examines one specific immune-system marker gene at high resolution, most often used before a bone marrow, stem cell, or organ transplant to see how closely a donor's tissue type matches the recipient's. Fine-grained matching on these markers helps predict how well a transplant will be tolerated. The test is run on a blood sample.

Rates data updated October 2026.

How much does High-Resolution Tissue-Type Test, Single Marker cost?

$120

Typical negotiated rate. In Florida, October 2026.

Insurers have agreed to pay about $120 for this service. The price depends on where it is billed: about $102 from a physician practice, and about $316 from a hospital or other facility.

These are rates insurers have negotiated with providers, not the amount a patient is billed. What you owe depends on your plan's deductible and coinsurance. Based on rates published by 8 insurance carriers under federal price transparency rules.

Prices by location type

Billed byTypicalRange
Physician practiceA doctor's office, clinic or independent provider$102$70.79 to $148
FacilityA hospital or hospital-owned outpatient department$316$214 to $316

How much rates vary

Facilitymedian $316 · 10th to 90th $129 to $316Professionalmedian $102 · 10th to 90th $54 to $195
$10$20$50$100$200$500facility $316professional $102

Distribution of negotiated rates across all payers (price axis is log-scale). Need provider-level prices or 24+ months of history? Contact us.

Rates by insurance carrier

Insurance Carrier
Aetna
Setting
Facility
Modifier
None
Typical Low
$77.62
Median
$128.82
Typical High
$263.03
Aetna
Setting
Professional
Modifier
None
Typical Low
$70.79
Median
$120.23
Typical High
$162.18
Aetna
Setting
Professional
Modifier
52 · Reduced service
Typical Low
$38.90
Median
$58.88
Typical High
$81.28
Aetna
Setting
Professional
Modifier
53 · Discontinued
Typical Low
$15.49
Median
$23.99
Typical High
$32.36
Ambetter
Setting
Professional
Modifier
None
Typical Low
$104.71
Median
$104.71
Typical High
$104.71
AvMed
Setting
Facility
Modifier
None
Typical Low
$134.90
Median
$169.82
Typical High
$208.93
AvMed
Setting
Professional
Modifier
None
Typical Low
$109.65
Median
$169.82
Typical High
$169.82
Cigna
Setting
Facility
Modifier
None
Typical Low
$69.18
Median
$131.83
Typical High
$691.83
Cigna
Setting
Professional
Modifier
None
Typical Low
$72.44
Median
$109.65
Typical High
$302.00
Florida Blue
Setting
Facility
Modifier
None
Typical Low
$316.23
Median
$316.23
Typical High
$316.23
Florida Blue
Setting
Professional
Modifier
None
Typical Low
$52.48
Median
$102.33
Typical High
$162.18
Molina
Setting
Professional
Modifier
None
Typical Low
$36.31
Median
$36.31
Typical High
$162.18
United
Setting
Facility
Modifier
None
Typical Low
$169.82
Median
$169.82
Typical High
$169.82
United
Setting
Professional
Modifier
None
Typical Low
$53.70
Median
$70.79
Typical High
$223.87
Wellpoint
Setting
Professional
Modifier
None
Typical Low
$158.49
Median
$169.82
Typical High
$169.82

Where Florida sits

The same service costs 3.5 times more in Alaska than in North Carolina. Every bar is a state, most expensive first. Touch or drag across it to read any state, then open that state for its carriers and full range.

Florida· 48th of 51

$120

AK $380NC $110

Median negotiated rate in each state, from every insurer that publishes one. States where no insurer publishes a rate for this service are not shown.