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High-Resolution Tissue-Type Test, Single Marker

Alabama rates for HCPCS 81381

This is a detailed genetic test that examines one specific immune-system marker gene at high resolution, most often used before a bone marrow, stem cell, or organ transplant to see how closely a donor's tissue type matches the recipient's. Fine-grained matching on these markers helps predict how well a transplant will be tolerated. The test is run on a blood sample.

Rates data updated October 2026.

How much does High-Resolution Tissue-Type Test, Single Marker cost?

$174

Typical negotiated rate. In Alabama, October 2026.

Insurers have agreed to pay about $174 for this service. The price depends on where it is billed: about $102 from a physician practice, and about $174 from a hospital or other facility.

These are rates insurers have negotiated with providers, not the amount a patient is billed. What you owe depends on your plan's deductible and coinsurance. Based on rates published by 4 insurance carriers under federal price transparency rules.

Prices by location type

Billed byTypicalRange
Physician practiceA doctor's office, clinic or independent provider$102$70.79 to $195
FacilityA hospital or hospital-owned outpatient department$174$174 to $174

How much rates vary

Facilitymedian $174 · 10th to 90th $174 to $174Professionalmedian $102 · 10th to 90th $71 to $195
$50$100$200$500facility $174professional $102

Distribution of negotiated rates across all payers (price axis is log-scale). Need provider-level prices or 24+ months of history? Contact us.

Rates by insurance carrier

Insurance Carrier
Aetna
Setting
Facility
Modifier
None
Typical Low
$194.98
Median
$194.98
Typical High
$263.03
Aetna
Setting
Professional
Modifier
None
Typical Low
$112.20
Median
$194.98
Typical High
$194.98
Aetna
Setting
Professional
Modifier
52 · Reduced service
Typical Low
$66.07
Median
$97.72
Typical High
$97.72
Aetna
Setting
Professional
Modifier
53 · Discontinued
Typical Low
$26.30
Median
$38.90
Typical High
$38.90
BCBS Alabama
Setting
Facility
Modifier
None
Typical Low
$173.78
Median
$173.78
Typical High
$173.78
BCBS Alabama
Setting
Professional
Modifier
21 + 22 · Increased work + 24 · Unrelated visit after surgery + 31
Typical Low
$66.07
Median
$95.50
Typical High
$95.50
Cigna
Setting
Facility
Modifier
None
Typical Low
$138.04
Median
$144.54
Typical High
$537.03
Cigna
Setting
Professional
Modifier
None
Typical Low
$48.98
Median
$77.62
Typical High
$537.03
United
Setting
Facility
Modifier
None
Typical Low
$61.66
Median
$151.36
Typical High
$169.82
United
Setting
Professional
Modifier
None
Typical Low
$70.79
Median
$70.79
Typical High
$102.33

Where Alabama sits

The same service costs 3.5 times more in Alaska than in North Carolina. Every bar is a state, most expensive first. Touch or drag across it to read any state, then open that state for its carriers and full range.

Alabama· 20th of 51

$174

AK $380NC $110

Median negotiated rate in each state, from every insurer that publishes one. States where no insurer publishes a rate for this service are not shown.