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Tissue Typing for Transplant Matching

South Dakota rates for HCPCS 81380

A laboratory test that identifies the HLA markers carried on a person's cells, using a blood sample. These markers differ greatly between people, and how closely they match between a donor and a recipient is a main factor in how well transplanted tissue is tolerated.

Rates data updated October 2026.

How much does Tissue Typing for Transplant Matching cost?

$204

Typical negotiated rate. In South Dakota, October 2026.

Insurers have agreed to pay about $204 for this service. The price depends on where it is billed: about $204 from a physician practice, and about $200 from a hospital or other facility.

These are rates insurers have negotiated with providers, not the amount a patient is billed. What you owe depends on your plan's deductible and coinsurance. Based on rates published by 6 insurance carriers under federal price transparency rules.

Prices by location type

Billed byTypicalRange
Physician practiceA doctor's office, clinic or independent provider$204$158 to $363
FacilityA hospital or hospital-owned outpatient department$200$200 to $339

How much rates vary

Facilitymedian $200 · 10th to 90th $166 to $339Professionalmedian $204 · 10th to 90th $117 to $427
$100$200$500$1Kfacility $200professional $204

Distribution of negotiated rates across all payers (price axis is log-scale). Small sample; interpret with caution. Need provider-level prices or 24+ months of history? Contact us.

Rates by insurance carrier

Insurance Carrier
Aetna
Setting
Facility
Modifier
None
Typical Low
$123.03
Median
$123.03
Typical High
$199.53
Aetna
Setting
Professional
Modifier
None
Typical Low
$117.49
Median
$117.49
Typical High
$165.96
Cigna
Setting
Facility
Modifier
None
Typical Low
$338.84
Median
$338.84
Typical High
$338.84
Cigna
Setting
Professional
Modifier
None
Typical Low
$204.17
Median
$338.84
Typical High
$426.58
Medica
Setting
Facility
Modifier
None
Typical Low
$169.82
Median
$199.53
Typical High
$281.84
Medica
Setting
Professional
Modifier
None
Typical Low
$107.15
Median
$158.49
Typical High
$363.08
Sanford Health Plan
Setting
Professional
Modifier
None
Typical Low
$288.40
Median
$416.87
Typical High
$489.78
United
Setting
Professional
Modifier
None
Typical Low
$74.13
Median
$123.03
Typical High
$239.88
Wellmark
Setting
Professional
Modifier
None
Typical Low
$177.83
Median
$177.83
Typical High
$177.83

Where South Dakota sits

The same service costs 3.4 times more in Alaska than in Delaware. Every bar is a state, most expensive first. Touch or drag across it to read any state, then open that state for its carriers and full range.

South Dakota· 18th of 51

$204

AK $398DE $117

Median negotiated rate in each state, from every insurer that publishes one. States where no insurer publishes a rate for this service are not shown.