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Tissue Typing for Transplant Matching

South Dakota rates for HCPCS 81380

A laboratory test that identifies the HLA markers carried on a person's cells, using a blood sample. These markers differ greatly between people, and how closely they match between a donor and a recipient is a main factor in how well transplanted tissue is tolerated.

Rates data updated July 2026.

How much does Tissue Typing for Transplant Matching cost?

$339

Typical negotiated rate. In South Dakota, July 2026.

Insurers have agreed to pay about $339 for this service. The price depends on where it is billed: about $288 from a physician practice, and about $339 from a hospital or other facility. The two figures are alternatives, not parts of one bill.

These are rates insurers have negotiated with providers, not the amount a patient is billed. What you owe depends on your plan's deductible and coinsurance. Based on rates published by 6 insurance carriers under federal price transparency rules.

Where it's billed changes the price

Billed byTypicalRange
Physician practiceA doctor's office, clinic or independent provider$288$138 to $427
FacilityA hospital or hospital-owned outpatient department$339$324 to $339

How much rates vary

Facilitymedian $339 · 10th to 90th $200 to $339Professionalmedian $288 · 10th to 90th $117 to $479
$100$200$500facility $339professional $288

Distribution of negotiated rates across all payers (price axis is log-scale). Each curve is scaled to its own total: facility and professional rates are different services, shown together to compare where they cluster. Need provider-level prices or 24+ months of history? Contact us.

Rates by insurance carrier

Insurance Carrier
Aetna
Setting
Facility
Modifier
Global
Typical Low
$123.03
Median
$199.53
Typical High
$199.53
Aetna
Setting
Professional
Modifier
Global
Typical Low
$117.49
Median
$138.04
Typical High
$165.96
Cigna
Setting
Facility
Modifier
Global
Typical Low
$338.84
Median
$338.84
Typical High
$338.84
Cigna
Setting
Professional
Modifier
Global
Typical Low
$257.04
Median
$338.84
Typical High
$426.58
Medica
Setting
Facility
Modifier
Global
Typical Low
$165.96
Median
$199.53
Typical High
$676.08
Medica
Setting
Professional
Modifier
Global
Typical Low
$107.15
Median
$123.03
Typical High
$891.25
Sanford Health Plan
Setting
Professional
Modifier
Global
Typical Low
$263.03
Median
$426.58
Typical High
$489.78
United
Setting
Professional
Modifier
Global
Typical Low
$74.13
Median
$123.03
Typical High
$239.88
Wellmark
Setting
Professional
Modifier
Global
Typical Low
$177.83
Median
$177.83
Typical High
$177.83

Where South Dakota sits

The same service costs 3.0 times more in Alaska than in Washington, DC. Every bar is a state, most expensive first. Touch or drag across it to read any state, then open that state for its carriers and full range.

South Dakota· 2nd of 51

$339

AK $398DC $132

Median negotiated rate in each state, from every insurer that publishes one. States where no insurer publishes a rate for this service are not shown.