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Tissue Typing for Transplant Matching

Massachusetts rates for HCPCS 81380

A laboratory test that identifies the HLA markers carried on a person's cells, using a blood sample. These markers differ greatly between people, and how closely they match between a donor and a recipient is a main factor in how well transplanted tissue is tolerated.

Rates data updated October 2026.

How much does Tissue Typing for Transplant Matching cost?

$209

Typical negotiated rate. In Massachusetts, October 2026.

Insurers have agreed to pay about $209 for this service. The price depends on where it is billed: about $178 from a physician practice, and about $269 from a hospital or other facility.

These are rates insurers have negotiated with providers, not the amount a patient is billed. What you owe depends on your plan's deductible and coinsurance. Based on rates published by 9 insurance carriers under federal price transparency rules.

Prices by location type

Billed byTypicalRange
Physician practiceA doctor's office, clinic or independent provider$178$145 to $447
FacilityA hospital or hospital-owned outpatient department$269$191 to $513

How much rates vary

Facilitymedian $269 · 10th to 90th $162 to $631Professionalmedian $178 · 10th to 90th $107 to $891
$100$200$500$1K$2K$5Kfacility $269professional $178

Distribution of negotiated rates across all payers (price axis is log-scale). Need provider-level prices or 24+ months of history? Contact us.

Rates by insurance carrier

Insurance Carrier
Aetna
Setting
Facility
Modifier
None
Typical Low
$169.82
Median
$338.84
Typical High
$758.58
Aetna
Setting
Professional
Modifier
None
Typical Low
$158.49
Median
$169.82
Typical High
$169.82
AllWays Health Partners
Setting
Facility
Modifier
None
Typical Low
$162.18
Median
$251.19
Typical High
$575.44
AllWays Health Partners
Setting
Professional
Modifier
None
Typical Low
$107.15
Median
$338.84
Typical High
$891.25
BCBS Massachusetts
Setting
Facility
Modifier
None
Typical Low
$346.74
Median
$489.78
Typical High
$691.83
BCBS Massachusetts
Setting
Professional
Modifier
None
Typical Low
$165.96
Median
$165.96
Typical High
$229.09
Cigna
Setting
Facility
Modifier
None
Typical Low
$138.04
Median
$239.88
Typical High
$371.54
Cigna
Setting
Professional
Modifier
None
Typical Low
$107.15
Median
$186.21
Typical High
$691.83
Fallon Health
Setting
Facility
Modifier
None
Typical Low
$83.18
Median
$302.00
Typical High
$5,888.44
Fallon Health
Setting
Professional
Modifier
None
Typical Low
$251.19
Median
$251.19
Typical High
$302.00
Harvard Pilgrim
Setting
Professional
Modifier
None
Typical Low
$107.15
Median
$177.83
Typical High
$562.34
Mass General Brigham
Setting
Facility
Modifier
None
Typical Low
$162.18
Median
$251.19
Typical High
$575.44
Mass General Brigham
Setting
Professional
Modifier
None
Typical Low
$107.15
Median
$338.84
Typical High
$891.25
United
Setting
Facility
Modifier
None
Typical Low
$158.49
Median
$177.83
Typical High
$213.80
United
Setting
Professional
Modifier
None
Typical Low
$70.79
Median
$107.15
Typical High
$354.81
Well Sense
Setting
Facility
Modifier
None
Typical Low
$154.88
Median
$218.78
Typical High
$323.59
Well Sense
Setting
Professional
Modifier
None
Typical Low
$181.97
Median
$181.97
Typical High
$218.78
3 more rates with less common billing modifiers

A modifier changes what was billed, for example a reduced or repeated service. Each of these modifiers carries under 10% of the published rates for this code. Modifier combinations, and modifiers with fewer than 30 rates for a carrier, are not listed.

Insurance Carrier
Aetna
Setting
Professional
Modifier
52 · Reduced service
Typical Low
$85.11
Median
$85.11
Typical High
$85.11
Aetna
Setting
Professional
Modifier
53 · Discontinued
Typical Low
$33.88
Median
$33.88
Typical High
$33.88
Fallon Health
Setting
Facility
Modifier
QW · Waived lab test
Typical Low
$177.83
Median
$229.09
Typical High
$275.42

Where Massachusetts sits

The same service costs 3.4 times more in Alaska than in Delaware. Every bar is a state, most expensive first. Touch or drag across it to read any state, then open that state for its carriers and full range.

Massachusetts· 16th of 51

$209

AK $398DE $117

Median negotiated rate in each state, from every insurer that publishes one. States where no insurer publishes a rate for this service are not shown.