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Basic Tissue Typing, Immune Cell Markers

Massachusetts rates for HCPCS 81375

A blood test that identifies a person's tissue type — the inherited identity tags the immune system uses to tell its own tissue from foreign tissue. This version covers the group of tags carried mainly on immune cells, read at a broad level that sorts each into its general family rather than pinpointing the exact version. It is used mainly when matching donors and recipients before a transplant.

Rates data updated October 2026.

How much does Basic Tissue Typing, Immune Cell Markers cost?

$263

Typical negotiated rate. In Massachusetts, October 2026.

Insurers have agreed to pay about $263 for this service. The price depends on where it is billed: about $219 from a physician practice, and about $331 from a hospital or other facility.

These are rates insurers have negotiated with providers, not the amount a patient is billed. What you owe depends on your plan's deductible and coinsurance. Based on rates published by 9 insurance carriers under federal price transparency rules.

Prices by location type

Billed byTypicalRange
Physician practiceA doctor's office, clinic or independent provider$219$182 to $562
FacilityA hospital or hospital-owned outpatient department$331$240 to $646

How much rates vary

Facilitymedian $331 · 10th to 90th $200 to $776Professionalmedian $219 · 10th to 90th $132 to $1,096
$100$200$500$1K$2K$5Kfacility $331professional $219

Distribution of negotiated rates across all payers (price axis is log-scale). Need provider-level prices or 24+ months of history? Contact us.

Rates by insurance carrier

Insurance Carrier
Aetna
Setting
Facility
Modifier
None
Typical Low
$208.93
Median
$416.87
Typical High
$933.25
Aetna
Setting
Professional
Modifier
None
Typical Low
$208.93
Median
$208.93
Typical High
$208.93
AllWays Health Partners
Setting
Facility
Modifier
None
Typical Low
$199.53
Median
$309.03
Typical High
$707.95
AllWays Health Partners
Setting
Professional
Modifier
None
Typical Low
$131.83
Median
$416.87
Typical High
$1,096.48
BCBS Massachusetts
Setting
Facility
Modifier
None
Typical Low
$436.52
Median
$616.60
Typical High
$870.96
BCBS Massachusetts
Setting
Professional
Modifier
None
Typical Low
$208.93
Median
$208.93
Typical High
$281.84
Cigna
Setting
Facility
Modifier
None
Typical Low
$173.78
Median
$302.00
Typical High
$467.74
Cigna
Setting
Professional
Modifier
None
Typical Low
$131.83
Median
$234.42
Typical High
$851.14
Fallon Health
Setting
Facility
Modifier
None
Typical Low
$83.18
Median
$371.54
Typical High
$5,888.44
Fallon Health
Setting
Professional
Modifier
None
Typical Low
$316.23
Median
$316.23
Typical High
$371.54
Harvard Pilgrim
Setting
Professional
Modifier
None
Typical Low
$131.83
Median
$218.78
Typical High
$707.95
Mass General Brigham
Setting
Facility
Modifier
None
Typical Low
$199.53
Median
$309.03
Typical High
$707.95
Mass General Brigham
Setting
Professional
Modifier
None
Typical Low
$131.83
Median
$416.87
Typical High
$1,096.48
United
Setting
Facility
Modifier
None
Typical Low
$199.53
Median
$218.78
Typical High
$263.03
United
Setting
Professional
Modifier
None
Typical Low
$89.13
Median
$131.83
Typical High
$446.68
Well Sense
Setting
Facility
Modifier
None
Typical Low
$194.98
Median
$269.15
Typical High
$398.11
Well Sense
Setting
Professional
Modifier
None
Typical Low
$229.09
Median
$229.09
Typical High
$275.42
3 more rates with less common billing modifiers

A modifier changes what was billed, for example a reduced or repeated service. Each of these modifiers carries under 10% of the published rates for this code. Modifier combinations, and modifiers with fewer than 30 rates for a carrier, are not listed.

Insurance Carrier
Aetna
Setting
Professional
Modifier
52 · Reduced service
Typical Low
$104.71
Median
$104.71
Typical High
$104.71
Aetna
Setting
Professional
Modifier
53 · Discontinued
Typical Low
$41.69
Median
$41.69
Typical High
$41.69
Fallon Health
Setting
Facility
Modifier
QW · Waived lab test
Typical Low
$218.78
Median
$288.40
Typical High
$338.84

Where Massachusetts sits

The same service costs 3.1 times more in Alaska than in New Jersey. Every bar is a state, most expensive first. Touch or drag across it to read any state, then open that state for its carriers and full range.

Massachusetts· 15th of 51

$263

AK $501NJ $162

Median negotiated rate in each state, from every insurer that publishes one. States where no insurer publishes a rate for this service are not shown.