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Tissue Typing For One Immune Marker

South Dakota rates for HCPCS 81374

A laboratory test that identifies one specific immune-system marker type from a person's DNA, at a broad level rather than pinning down its exact subtype. These markers, carried on the surface of cells, are compared between donor and recipient to judge how well they match before a transplant. The same typing is also used to look for a marker linked to particular immune-related conditions or to a risk of severe reaction to certain medicines.

Rates data updated July 2026.

How much does Tissue Typing For One Immune Marker cost?

$112

Typical negotiated rate. In South Dakota, July 2026.

Insurers have agreed to pay about $112 for this service. The price depends on where it is billed: about $77.62 from a physician practice, and about $141 from a hospital or other facility. The two figures are alternatives, not parts of one bill.

These are rates insurers have negotiated with providers, not the amount a patient is billed. What you owe depends on your plan's deductible and coinsurance. Based on rates published by 7 insurance carriers under federal price transparency rules.

Where it's billed changes the price

Billed byTypicalRange
Physician practiceA doctor's office, clinic or independent provider$77.62$74.13 to $141
FacilityA hospital or hospital-owned outpatient department$141$141 to $182

How much rates vary

Facilitymedian $141 · 10th to 90th $85 to $182Professionalmedian $78 · 10th to 90th $51 to $178
$50$100$200facility $141professional $78

Distribution of negotiated rates across all payers (price axis is log-scale). Each curve is scaled to its own total: facility and professional rates are different services, shown together to compare where they cluster. Need provider-level prices or 24+ months of history? Contact us.

Rates by insurance carrier

Insurance Carrier
Aetna
Setting
Facility
Modifier
Global
Typical Low
$85.11
Median
$181.97
Typical High
$181.97
Aetna
Setting
Professional
Modifier
Global
Typical Low
$50.12
Median
$75.86
Typical High
$125.89
Avera
Setting
Professional
Modifier
Global
Typical Low
$77.62
Median
$77.62
Typical High
$77.62
Cigna
Setting
Facility
Modifier
Global
Typical Low
$141.25
Median
$141.25
Typical High
$141.25
Cigna
Setting
Professional
Modifier
Global
Typical Low
$107.15
Median
$141.25
Typical High
$177.83
Medica
Setting
Facility
Modifier
Global
Typical Low
$70.79
Median
$85.11
Typical High
$275.42
Medica
Setting
Professional
Modifier
Global
Typical Low
$44.67
Median
$51.29
Typical High
$371.54
Sanford Health Plan
Setting
Professional
Modifier
Global
Typical Low
$112.20
Median
$177.83
Typical High
$204.17
United
Setting
Professional
Modifier
Global
Typical Low
$30.90
Median
$51.29
Typical High
$100.00
Wellmark
Setting
Professional
Modifier
Global
Typical Low
$74.13
Median
$74.13
Typical High
$74.13

Where South Dakota sits

The same service costs 3.5 times more in Nebraska than in Washington, DC. Every bar is a state, most expensive first. Touch or drag across it to read any state, then open that state for its carriers and full range.

South Dakota· 8th of 51

$112

NE $195DC $56.23

Median negotiated rate in each state, from every insurer that publishes one. States where no insurer publishes a rate for this service are not shown.