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Genetic Test For A Gene Linked To Sickle Cell Disease

South Dakota rates for HCPCS 81364

A genetic blood test that examines the gene associated with sickle cell disease and beta thalassemia, two inherited conditions affecting red blood cells and the hemoglobin they carry. It looks for a change in this gene that can cause or contribute to these conditions. It may be used to confirm a diagnosis, guide family planning, or evaluate a newborn or family member of someone already diagnosed.

Rates data updated October 2026.

How much does Genetic Test For A Gene Linked To Sickle Cell Disease cost?

$372

Typical negotiated rate. In South Dakota, October 2026.

Insurers have agreed to pay about $372 for this service. The price depends on where it is billed: about $324 from a physician practice, and about $372 from a hospital or other facility.

These are rates insurers have negotiated with providers, not the amount a patient is billed. What you owe depends on your plan's deductible and coinsurance. Based on rates published by 6 insurance carriers under federal price transparency rules.

Prices by location type

Billed byTypicalRange
Physician practiceA doctor's office, clinic or independent provider$324$229 to $617
FacilityA hospital or hospital-owned outpatient department$372$372 to $617

How much rates vary

Facilitymedian $372 · 10th to 90th $309 to $617Professionalmedian $324 · 10th to 90th $166 to $776
$200$500$1K$2K$5Kfacility $372professional $324

Distribution of negotiated rates across all payers (price axis is log-scale). Small sample; interpret with caution. Need provider-level prices or 24+ months of history? Contact us.

Rates by insurance carrier

Insurance Carrier
Aetna
Setting
Facility
Modifier
None
Typical Low
$229.09
Median
$229.09
Typical High
$371.54
Aetna
Setting
Professional
Modifier
None
Typical Low
$218.78
Median
$218.78
Typical High
$302.00
Cigna
Setting
Facility
Modifier
None
Typical Low
$616.60
Median
$616.60
Typical High
$616.60
Cigna
Setting
Professional
Modifier
None
Typical Low
$371.54
Median
$616.60
Typical High
$776.25
Medica
Setting
Facility
Modifier
None
Typical Low
$309.03
Median
$371.54
Typical High
$602.56
Medica
Setting
Professional
Modifier
None
Typical Low
$165.96
Median
$295.12
Typical High
$588.84
Sanford Health Plan
Setting
Professional
Modifier
None
Typical Low
$489.78
Median
$758.58
Typical High
$891.25
United
Setting
Professional
Modifier
None
Typical Low
$134.90
Median
$194.98
Typical High
$323.59
Wellmark
Setting
Professional
Modifier
None
Typical Low
$323.59
Median
$323.59
Typical High
$323.59

Where South Dakota sits

The same service costs 4.2 times more in Alaska than in Alabama. Every bar is a state, most expensive first. Touch or drag across it to read any state, then open that state for its carriers and full range.

South Dakota· 10th of 51

$372

AK $724AL $174

Median negotiated rate in each state, from every insurer that publishes one. States where no insurer publishes a rate for this service are not shown.