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Genetic Test For A Gene Linked To Sickle Cell Disease

Missouri rates for HCPCS 81364

A genetic blood test that examines the gene associated with sickle cell disease and beta thalassemia, two inherited conditions affecting red blood cells and the hemoglobin they carry. It looks for a change in this gene that can cause or contribute to these conditions. It may be used to confirm a diagnosis, guide family planning, or evaluate a newborn or family member of someone already diagnosed.

Rates data updated October 2026.

How much does Genetic Test For A Gene Linked To Sickle Cell Disease cost?

$316

Typical negotiated rate. In Missouri, October 2026.

Insurers have agreed to pay about $316 for this service. The price depends on where it is billed: about $282 from a physician practice, and about $562 from a hospital or other facility.

These are rates insurers have negotiated with providers, not the amount a patient is billed. What you owe depends on your plan's deductible and coinsurance. Based on rates published by 6 insurance carriers under federal price transparency rules.

Prices by location type

Billed byTypicalRange
Physician practiceA doctor's office, clinic or independent provider$282$195 to $513
FacilityA hospital or hospital-owned outpatient department$562$331 to $832

How much rates vary

Facilitymedian $562 · 10th to 90th $295 to $1,549Professionalmedian $282 · 10th to 90th $162 to $851
$200$500$1K$2Kfacility $562professional $282

Distribution of negotiated rates across all payers (price axis is log-scale). Need provider-level prices or 24+ months of history? Contact us.

Rates by insurance carrier

Insurance Carrier
Aetna
Setting
Facility
Modifier
None
Typical Low
$275.42
Median
$416.87
Typical High
$602.56
Aetna
Setting
Professional
Modifier
None
Typical Low
$275.42
Median
$281.84
Typical High
$346.74
Anthem BCBS
Setting
Facility
Modifier
None
Typical Low
$323.59
Median
$323.59
Typical High
$1,513.56
Anthem BCBS
Setting
Professional
Modifier
None
Typical Low
$194.98
Median
$309.03
Typical High
$588.84
BCBS Kansas City
Setting
Professional
Modifier
None
Typical Low
$229.09
Median
$323.59
Typical High
$616.60
Cigna
Setting
Facility
Modifier
None
Typical Low
$331.13
Median
$707.95
Typical High
$1,659.59
Cigna
Setting
Professional
Modifier
None
Typical Low
$138.04
Median
$257.04
Typical High
$416.87
Medica
Setting
Facility
Modifier
None
Typical Low
$295.12
Median
$562.34
Typical High
$1,548.82
Medica
Setting
Professional
Modifier
None
Typical Low
$162.18
Median
$338.84
Typical High
$1,621.81
United
Setting
Facility
Modifier
None
Typical Low
$295.12
Median
$295.12
Typical High
$295.12
United
Setting
Professional
Modifier
None
Typical Low
$134.90
Median
$194.98
Typical High
$436.52
2 more rates with less common billing modifiers

A modifier changes what was billed, for example a reduced or repeated service. Each of these modifiers carries under 10% of the published rates for this code. Modifier combinations, and modifiers with fewer than 30 rates for a carrier, are not listed.

Insurance Carrier
Aetna
Setting
Professional
Modifier
52 · Reduced service
Typical Low
$138.04
Median
$138.04
Typical High
$186.21
Aetna
Setting
Professional
Modifier
53 · Discontinued
Typical Low
$54.95
Median
$56.23
Typical High
$74.13

Where Missouri sits

The same service costs 4.2 times more in Alaska than in Alabama. Every bar is a state, most expensive first. Touch or drag across it to read any state, then open that state for its carriers and full range.

Missouri· 28th of 51

$316

AK $724AL $174

Median negotiated rate in each state, from every insurer that publishes one. States where no insurer publishes a rate for this service are not shown.