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Genetic Test For A Gene Linked To Sickle Cell Disease

Maryland rates for HCPCS 81364

A genetic blood test that examines the gene associated with sickle cell disease and beta thalassemia, two inherited conditions affecting red blood cells and the hemoglobin they carry. It looks for a change in this gene that can cause or contribute to these conditions. It may be used to confirm a diagnosis, guide family planning, or evaluate a newborn or family member of someone already diagnosed.

Rates data updated October 2026.

How much does Genetic Test For A Gene Linked To Sickle Cell Disease cost?

$240

Typical negotiated rate. In Maryland, October 2026.

Insurers have agreed to pay about $240 for this service. Most negotiated rates run $195 to $257.

These are rates insurers have negotiated with providers, not the amount a patient is billed. What you owe depends on your plan's deductible and coinsurance. Based on rates published by 6 insurance carriers under federal price transparency rules.

How much rates vary

Professionalmedian $240 · 10th to 90th $145 to $324
$200$500$1Kprofessional $240

Distribution of negotiated rates across all payers (price axis is log-scale). Need provider-level prices or 24+ months of history? Contact us.

Rates by insurance carrier

Insurance Carrier
Aetna
Setting
Professional
Modifier
None
Typical Low
$208.93
Median
$245.47
Typical High
$269.15
CareFirst
Setting
Professional
Modifier
None
Typical Low
$234.42
Median
$257.04
Typical High
$257.04
Cigna
Setting
Professional
Modifier
None
Typical Low
$169.82
Median
$229.09
Typical High
$933.25
Kaiser Permanente
Setting
Professional
Modifier
None
Typical Low
$323.59
Median
$389.05
Typical High
$489.78
United
Setting
Professional
Modifier
None
Typical Low
$134.90
Median
$162.18
Typical High
$281.84
Wellpoint
Setting
Professional
Modifier
None
Typical Low
$162.18
Median
$162.18
Typical High
$257.04
2 more rates with less common billing modifiers

A modifier changes what was billed, for example a reduced or repeated service. Each of these modifiers carries under 10% of the published rates for this code. Modifier combinations, and modifiers with fewer than 30 rates for a carrier, are not listed.

Insurance Carrier
Aetna
Setting
Professional
Modifier
52 · Reduced service
Typical Low
$120.23
Median
$123.03
Typical High
$131.83
Aetna
Setting
Professional
Modifier
53 · Discontinued
Typical Low
$47.86
Median
$48.98
Typical High
$53.70

Where Maryland sits

The same service costs 4.2 times more in Alaska than in Alabama. Every bar is a state, most expensive first. Touch or drag across it to read any state, then open that state for its carriers and full range.

Maryland· 46th of 51

$240

AK $724AL $174

Median negotiated rate in each state, from every insurer that publishes one. States where no insurer publishes a rate for this service are not shown.