go back

Genetic Test For A Gene Linked To Sickle Cell Disease

Massachusetts rates for HCPCS 81364

A genetic blood test that examines the gene associated with sickle cell disease and beta thalassemia, two inherited conditions affecting red blood cells and the hemoglobin they carry. It looks for a change in this gene that can cause or contribute to these conditions. It may be used to confirm a diagnosis, guide family planning, or evaluate a newborn or family member of someone already diagnosed.

Rates data updated October 2026.

How much does Genetic Test For A Gene Linked To Sickle Cell Disease cost?

$339

Typical negotiated rate. In Massachusetts, October 2026.

Insurers have agreed to pay about $339 for this service. The price depends on where it is billed: about $324 from a physician practice, and about $468 from a hospital or other facility.

These are rates insurers have negotiated with providers, not the amount a patient is billed. What you owe depends on your plan's deductible and coinsurance. Based on rates published by 9 insurance carriers under federal price transparency rules.

Prices by location type

Billed byTypicalRange
Physician practiceA doctor's office, clinic or independent provider$324$195 to $813
FacilityA hospital or hospital-owned outpatient department$468$339 to $759

How much rates vary

Facilitymedian $468 · 10th to 90th $240 to $1,047Professionalmedian $324 · 10th to 90th $195 to $1,622
$100$200$500$1K$2K$5Kfacility $468professional $324

Distribution of negotiated rates across all payers (price axis is log-scale). Need provider-level prices or 24+ months of history? Contact us.

Rates by insurance carrier

Insurance Carrier
Aetna
Setting
Facility
Modifier
None
Typical Low
$229.09
Median
$457.09
Typical High
$1,023.29
Aetna
Setting
Professional
Modifier
None
Typical Low
$229.09
Median
$229.09
Typical High
$263.03
AllWays Health Partners
Setting
Facility
Modifier
None
Typical Low
$239.88
Median
$371.54
Typical High
$1,000.00
AllWays Health Partners
Setting
Professional
Modifier
None
Typical Low
$194.98
Median
$660.69
Typical High
$1,621.81
BCBS Massachusetts
Setting
Facility
Modifier
None
Typical Low
$380.19
Median
$645.65
Typical High
$1,148.15
BCBS Massachusetts
Setting
Professional
Modifier
None
Typical Low
$302.00
Median
$302.00
Typical High
$302.00
Cigna
Setting
Facility
Modifier
None
Typical Low
$208.93
Median
$257.04
Typical High
$630.96
Cigna
Setting
Professional
Modifier
None
Typical Low
$181.97
Median
$354.81
Typical High
$1,258.93
Fallon Health
Setting
Facility
Modifier
None
Typical Low
$169.82
Median
$549.54
Typical High
$5,888.44
Fallon Health
Setting
Professional
Modifier
None
Typical Low
$467.74
Median
$467.74
Typical High
$549.54
Harvard Pilgrim
Setting
Professional
Modifier
None
Typical Low
$194.98
Median
$323.59
Typical High
$851.14
Mass General Brigham
Setting
Facility
Modifier
None
Typical Low
$239.88
Median
$371.54
Typical High
$1,000.00
Mass General Brigham
Setting
Professional
Modifier
None
Typical Low
$194.98
Median
$660.69
Typical High
$1,621.81
United
Setting
Facility
Modifier
None
Typical Low
$295.12
Median
$323.59
Typical High
$389.05
United
Setting
Professional
Modifier
None
Typical Low
$128.82
Median
$194.98
Typical High
$616.60
Well Sense
Setting
Facility
Modifier
None
Typical Low
$288.40
Median
$398.11
Typical High
$588.84
Well Sense
Setting
Professional
Modifier
None
Typical Low
$239.88
Median
$239.88
Typical High
$288.40
3 more rates with less common billing modifiers

A modifier changes what was billed, for example a reduced or repeated service. Each of these modifiers carries under 10% of the published rates for this code. Modifier combinations, and modifiers with fewer than 30 rates for a carrier, are not listed.

Insurance Carrier
Aetna
Setting
Professional
Modifier
52 · Reduced service
Typical Low
$114.82
Median
$114.82
Typical High
$114.82
Aetna
Setting
Professional
Modifier
53 · Discontinued
Typical Low
$45.71
Median
$45.71
Typical High
$45.71
Fallon Health
Setting
Facility
Modifier
QW · Waived lab test
Typical Low
$323.59
Median
$426.58
Typical High
$501.19

Where Massachusetts sits

The same service costs 4.2 times more in Alaska than in Alabama. Every bar is a state, most expensive first. Touch or drag across it to read any state, then open that state for its carriers and full range.

Massachusetts· 18th of 51

$339

AK $724AL $174

Median negotiated rate in each state, from every insurer that publishes one. States where no insurer publishes a rate for this service are not shown.