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Genetic Test For A Gene Linked To Sickle Cell Disease

Illinois rates for HCPCS 81364

A genetic blood test that examines the gene associated with sickle cell disease and beta thalassemia, two inherited conditions affecting red blood cells and the hemoglobin they carry. It looks for a change in this gene that can cause or contribute to these conditions. It may be used to confirm a diagnosis, guide family planning, or evaluate a newborn or family member of someone already diagnosed.

Rates data updated October 2026.

How much does Genetic Test For A Gene Linked To Sickle Cell Disease cost?

$251

Typical negotiated rate. In Illinois, October 2026.

Insurers have agreed to pay about $251 for this service. The price depends on where it is billed: about $224 from a physician practice, and about $676 from a hospital or other facility.

These are rates insurers have negotiated with providers, not the amount a patient is billed. What you owe depends on your plan's deductible and coinsurance. Based on rates published by 5 insurance carriers under federal price transparency rules.

Prices by location type

Billed byTypicalRange
Physician practiceA doctor's office, clinic or independent provider$224$4.47 to $257
FacilityA hospital or hospital-owned outpatient department$676$437 to $1,230

How much rates vary

Facilitymedian $676 · 10th to 90th $363 to $2,344Professionalmedian $224 · 10th to 90th $3 to $427
$10$100$1Kfacility $676professional $224

Distribution of negotiated rates across all payers (price axis is log-scale). Need provider-level prices or 24+ months of history? Contact us.

Rates by insurance carrier

Insurance Carrier
Aetna
Setting
Facility
Modifier
None
Typical Low
$269.15
Median
$524.81
Typical High
$977.24
Aetna
Setting
Professional
Modifier
None
Typical Low
$251.19
Median
$269.15
Typical High
$295.12
BCBS Illinois
Setting
Facility
Modifier
None
Typical Low
$389.05
Median
$562.34
Typical High
$4,073.80
BCBS Illinois
Setting
Professional
Modifier
None
Typical Low
$3.47
Median
$223.87
Typical High
$251.19
Cigna
Setting
Facility
Modifier
None
Typical Low
$363.08
Median
$776.25
Typical High
$1,412.54
Cigna
Setting
Professional
Modifier
None
Typical Low
$147.91
Median
$380.19
Typical High
$537.03
Hally Health
Setting
Professional
Modifier
None
Typical Low
$338.84
Median
$501.19
Typical High
$1,122.02
Hally Health
Setting
Facility
Modifier
None
Typical Low
$100.00
Median
$100.00
Typical High
$100.00
Hally Health
Setting
Professional
Modifier
None
Typical Low
$426.58
Median
$426.58
Typical High
$426.58
United
Setting
Facility
Modifier
None
Typical Low
$323.59
Median
$389.05
Typical High
$407.38
United
Setting
Professional
Modifier
None
Typical Low
$134.90
Median
$194.98
Typical High
$331.13
4 more rates with less common billing modifiers

A modifier changes what was billed, for example a reduced or repeated service. Each of these modifiers carries under 10% of the published rates for this code. Modifier combinations, and modifiers with fewer than 30 rates for a carrier, are not listed.

Insurance Carrier
Aetna
Setting
Facility
Modifier
52 · Reduced service
Typical Low
$131.83
Median
$257.04
Typical High
$489.78
Aetna
Setting
Facility
Modifier
53 · Discontinued
Typical Low
$53.70
Median
$102.33
Typical High
$194.98
Aetna
Setting
Professional
Modifier
52 · Reduced service
Typical Low
$131.83
Median
$131.83
Typical High
$144.54
Aetna
Setting
Professional
Modifier
53 · Discontinued
Typical Low
$53.70
Median
$53.70
Typical High
$58.88

Where Illinois sits

The same service costs 4.2 times more in Alaska than in Alabama. Every bar is a state, most expensive first. Touch or drag across it to read any state, then open that state for its carriers and full range.

Illinois· 42nd of 51

$251

AK $724AL $174

Median negotiated rate in each state, from every insurer that publishes one. States where no insurer publishes a rate for this service are not shown.