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VKORC1 Warfarin Sensitivity Gene Test

Missouri rates for HCPCS 81355

A genetic test that checks for the common changes in the VKORC1 gene, which affects how strongly a person responds to the blood thinner warfarin. People carrying certain versions need a lower or a higher dose to reach a safe level of blood thinning. A blood or saliva sample is used.

Rates data updated October 2026.

How much does VKORC1 Warfarin Sensitivity Gene Test cost?

$85.11

Typical negotiated rate. In Missouri, October 2026.

Insurers have agreed to pay about $85.11 for this service. The price depends on where it is billed: about $75.86 from a physician practice, and about $155 from a hospital or other facility.

These are rates insurers have negotiated with providers, not the amount a patient is billed. What you owe depends on your plan's deductible and coinsurance. Based on rates published by 6 insurance carriers under federal price transparency rules.

Prices by location type

Billed byTypicalRange
Physician practiceA doctor's office, clinic or independent provider$75.86$54.95 to $141
FacilityA hospital or hospital-owned outpatient department$155$89.13 to $214

How much rates vary

Facilitymedian $155 · 10th to 90th $76 to $417Professionalmedian $76 · 10th to 90th $44 to $229
$20$50$100$200$500facility $155professional $76

Distribution of negotiated rates across all payers (price axis is log-scale). Need provider-level prices or 24+ months of history? Contact us.

Rates by insurance carrier

Insurance Carrier
Aetna
Setting
Facility
Modifier
None
Typical Low
$74.13
Median
$114.82
Typical High
$162.18
Aetna
Setting
Professional
Modifier
None
Typical Low
$64.57
Median
$75.86
Typical High
$102.33
Anthem BCBS
Setting
Facility
Modifier
None
Typical Low
$89.13
Median
$89.13
Typical High
$407.38
Anthem BCBS
Setting
Professional
Modifier
None
Typical Low
$54.95
Median
$74.13
Typical High
$158.49
BCBS Kansas City
Setting
Facility
Modifier
None
Typical Low
$123.03
Median
$134.90
Typical High
$239.88
BCBS Kansas City
Setting
Professional
Modifier
None
Typical Low
$61.66
Median
$89.13
Typical High
$165.96
Cigna
Setting
Facility
Modifier
None
Typical Low
$66.07
Median
$186.21
Typical High
$281.84
Cigna
Setting
Professional
Modifier
None
Typical Low
$41.69
Median
$85.11
Typical High
$114.82
Medica
Setting
Facility
Modifier
None
Typical Low
$79.43
Median
$154.88
Typical High
$416.87
Medica
Setting
Professional
Modifier
None
Typical Low
$43.65
Median
$91.20
Typical High
$436.52
United
Setting
Facility
Modifier
None
Typical Low
$79.43
Median
$79.43
Typical High
$79.43
United
Setting
Professional
Modifier
None
Typical Low
$37.15
Median
$52.48
Typical High
$117.49
2 more rates with less common billing modifiers

A modifier changes what was billed, for example a reduced or repeated service. Each of these modifiers carries under 10% of the published rates for this code. Modifier combinations, and modifiers with fewer than 30 rates for a carrier, are not listed.

Insurance Carrier
Aetna
Setting
Professional
Modifier
52 · Reduced service
Typical Low
$37.15
Median
$38.02
Typical High
$51.29
Aetna
Setting
Professional
Modifier
53 · Discontinued
Typical Low
$15.14
Median
$15.14
Typical High
$20.42

Where Missouri sits

The same service costs 3.8 times more in Alaska than in Florida. Every bar is a state, most expensive first. Touch or drag across it to read any state, then open that state for its carriers and full range.

Missouri· 27th of 51

$85.11

AK $200FL $52.48

Median negotiated rate in each state, from every insurer that publishes one. States where no insurer publishes a rate for this service are not shown.