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VKORC1 Warfarin Sensitivity Gene Test

Massachusetts rates for HCPCS 81355

A genetic test that checks for the common changes in the VKORC1 gene, which affects how strongly a person responds to the blood thinner warfarin. People carrying certain versions need a lower or a higher dose to reach a safe level of blood thinning. A blood or saliva sample is used.

Rates data updated October 2026.

How much does VKORC1 Warfarin Sensitivity Gene Test cost?

$93.33

Typical negotiated rate. In Massachusetts, October 2026.

Insurers have agreed to pay about $93.33 for this service. The price depends on where it is billed: about $89.13 from a physician practice, and about $155 from a hospital or other facility.

These are rates insurers have negotiated with providers, not the amount a patient is billed. What you owe depends on your plan's deductible and coinsurance. Based on rates published by 9 insurance carriers under federal price transparency rules.

Prices by location type

Billed byTypicalRange
Physician practiceA doctor's office, clinic or independent provider$89.13$52.48 to $229
FacilityA hospital or hospital-owned outpatient department$155$117 to $245

How much rates vary

Facilitymedian $155 · 10th to 90th $89 to $302Professionalmedian $89 · 10th to 90th $50 to $437
$50$100$200$500$1K$2K$5Kfacility $155professional $89

Distribution of negotiated rates across all payers (price axis is log-scale). Need provider-level prices or 24+ months of history? Contact us.

Rates by insurance carrier

Insurance Carrier
Aetna
Setting
Facility
Modifier
None
Typical Low
$50.12
Median
$50.12
Typical High
$50.12
Aetna
Setting
Professional
Modifier
None
Typical Low
$50.12
Median
$50.12
Typical High
$50.12
AllWays Health Partners
Setting
Facility
Modifier
None
Typical Low
$97.72
Median
$245.47
Typical High
$302.00
AllWays Health Partners
Setting
Professional
Modifier
None
Typical Low
$52.48
Median
$169.82
Typical High
$436.52
BCBS Massachusetts
Setting
Facility
Modifier
None
Typical Low
$141.25
Median
$199.53
Typical High
$281.84
BCBS Massachusetts
Setting
Professional
Modifier
None
Typical Low
$26.30
Median
$26.30
Typical High
$26.30
Cigna
Setting
Facility
Modifier
None
Typical Low
$56.23
Median
$97.72
Typical High
$173.78
Cigna
Setting
Professional
Modifier
None
Typical Low
$52.48
Median
$93.33
Typical High
$346.74
Fallon Health
Setting
Facility
Modifier
None
Typical Low
$83.18
Median
$147.91
Typical High
$5,888.44
Fallon Health
Setting
Professional
Modifier
None
Typical Low
$125.89
Median
$125.89
Typical High
$147.91
Harvard Pilgrim
Setting
Professional
Modifier
None
Typical Low
$52.48
Median
$89.13
Typical High
$223.87
Mass General Brigham
Setting
Facility
Modifier
None
Typical Low
$97.72
Median
$245.47
Typical High
$302.00
Mass General Brigham
Setting
Professional
Modifier
None
Typical Low
$52.48
Median
$169.82
Typical High
$436.52
United
Setting
Facility
Modifier
None
Typical Low
$79.43
Median
$89.13
Typical High
$104.71
United
Setting
Professional
Modifier
None
Typical Low
$35.48
Median
$52.48
Typical High
$169.82
Well Sense
Setting
Facility
Modifier
None
Typical Low
$77.62
Median
$107.15
Typical High
$158.49
Well Sense
Setting
Professional
Modifier
None
Typical Low
$2,511.89
Median
$2,511.89
Typical High
$3,019.95
3 more rates with less common billing modifiers

A modifier changes what was billed, for example a reduced or repeated service. Each of these modifiers carries under 10% of the published rates for this code. Modifier combinations, and modifiers with fewer than 30 rates for a carrier, are not listed.

Insurance Carrier
Aetna
Setting
Professional
Modifier
52 · Reduced service
Typical Low
$25.12
Median
$25.12
Typical High
$25.12
Aetna
Setting
Professional
Modifier
53 · Discontinued
Typical Low
$10.00
Median
$10.00
Typical High
$10.00
Fallon Health
Setting
Facility
Modifier
QW · Waived lab test
Typical Low
$89.13
Median
$114.82
Typical High
$138.04

Where Massachusetts sits

The same service costs 3.8 times more in Alaska than in Florida. Every bar is a state, most expensive first. Touch or drag across it to read any state, then open that state for its carriers and full range.

Massachusetts· 17th of 51

$93.33

AK $200FL $52.48

Median negotiated rate in each state, from every insurer that publishes one. States where no insurer publishes a rate for this service are not shown.