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Genetic Test for Changes in a Single Gene

South Dakota rates for HCPCS 81352

A laboratory test that examines DNA from a blood or tissue sample to look for changes in one specific gene. The result is used to help confirm a diagnosis, assess risk, or guide treatment decisions, and is normally interpreted alongside personal and family medical history.

Rates data updated July 2026.

How much does Genetic Test for Changes in a Single Gene cost?

$631

Typical negotiated rate. In South Dakota, July 2026.

Insurers have agreed to pay about $631 for this service. The price depends on where it is billed: about $398 from a physician practice, and about $851 from a hospital or other facility. The two figures are alternatives, not parts of one bill.

These are rates insurers have negotiated with providers, not the amount a patient is billed. What you owe depends on your plan's deductible and coinsurance. Based on rates published by 7 insurance carriers under federal price transparency rules.

Where it's billed changes the price

Billed byTypicalRange
Physician practiceA doctor's office, clinic or independent provider$398$257 to $776
FacilityA hospital or hospital-owned outpatient department$851$631 to $851

How much rates vary

Facilitymedian $851 · 10th to 90th $525 to $851Professionalmedian $398 · 10th to 90th $219 to $794
$200$500$1Kfacility $851professional $398

Distribution of negotiated rates across all payers (price axis is log-scale). Each curve is scaled to its own total: facility and professional rates are different services, shown together to compare where they cluster. Need provider-level prices or 24+ months of history? Contact us.

Rates by insurance carrier

Insurance Carrier
Aetna
Setting
Facility
Modifier
Global
Typical Low
$630.96
Median
$851.14
Typical High
$851.14
Aetna
Setting
Professional
Modifier
Global
Typical Low
$218.78
Median
$257.04
Typical High
$309.03
Avera
Setting
Facility
Modifier
Global
Typical Low
$331.13
Median
$331.13
Typical High
$489.78
Cigna
Setting
Facility
Modifier
Global
Typical Low
$630.96
Median
$630.96
Typical High
$630.96
Cigna
Setting
Professional
Modifier
Global
Typical Low
$398.11
Median
$630.96
Typical High
$794.33
Medica
Setting
Facility
Modifier
Global
Typical Low
$309.03
Median
$371.54
Typical High
$602.56
Medica
Setting
Professional
Modifier
Global
Typical Low
$169.82
Median
$169.82
Typical High
$1,659.59
Sanford Health Plan
Setting
Professional
Modifier
Global
Typical Low
$467.74
Median
$776.25
Typical High
$912.01
United
Setting
Professional
Modifier
Global
Typical Low
$138.04
Median
$199.53
Typical High
$436.52
Wellmark
Setting
Professional
Modifier
Global
Typical Low
$331.13
Median
$331.13
Typical High
$331.13

Where South Dakota sits

The same service costs 3.4 times more in Alaska than in Delaware. Every bar is a state, most expensive first. Touch or drag across it to read any state, then open that state for its carriers and full range.

South Dakota· 2nd of 51

$631

AK $741DE $219

Median negotiated rate in each state, from every insurer that publishes one. States where no insurer publishes a rate for this service are not shown.