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Genetic Test for Changes in a Single Gene

South Carolina rates for HCPCS 81352

A laboratory test that examines DNA from a blood or tissue sample to look for changes in one specific gene. The result is used to help confirm a diagnosis, assess risk, or guide treatment decisions, and is normally interpreted alongside personal and family medical history.

Rates data updated July 2026.

How much does Genetic Test for Changes in a Single Gene cost?

$263

Typical negotiated rate. In South Carolina, July 2026.

Insurers have agreed to pay about $263 for this service. The price depends on where it is billed: about $257 from a physician practice, and about $813 from a hospital or other facility. The two figures are alternatives, not parts of one bill.

These are rates insurers have negotiated with providers, not the amount a patient is billed. What you owe depends on your plan's deductible and coinsurance. Based on rates published by 5 insurance carriers under federal price transparency rules.

Where it's billed changes the price

Billed byTypicalRange
Physician practiceA doctor's office, clinic or independent provider$257$257 to $288
FacilityA hospital or hospital-owned outpatient department$813$263 to $1,047

How much rates vary

Facilitymedian $813 · 10th to 90th $257 to $1,549Professionalmedian $257 · 10th to 90th $200 to $347
$200$500$1Kfacility $813professional $257

Distribution of negotiated rates across all payers (price axis is log-scale). Each curve is scaled to its own total: facility and professional rates are different services, shown together to compare where they cluster. Need provider-level prices or 24+ months of history? Contact us.

Rates by insurance carrier

Insurance Carrier
Aetna
Setting
Facility
Modifier
Global
Typical Low
$257.04
Median
$812.83
Typical High
$1,548.82
Aetna
Setting
Professional
Modifier
Global
Typical Low
$257.04
Median
$257.04
Typical High
$309.03
BCBS
Setting
Professional
Modifier
Global
Typical Low
$331.13
Median
$354.81
Typical High
$588.84
Cigna
Setting
Facility
Modifier
Global
Typical Low
$616.60
Median
$1,071.52
Typical High
$1,862.09
Cigna
Setting
Professional
Modifier
Global
Typical Low
$147.91
Median
$162.18
Typical High
$398.11
Medcost
Setting
Facility
Modifier
Global
Typical Low
$257.04
Median
$295.12
Typical High
$436.52
United
Setting
Facility
Modifier
Global
Typical Low
$295.12
Median
$331.13
Typical High
$398.11
United
Setting
Professional
Modifier
Global
Typical Low
$138.04
Median
$199.53
Typical High
$331.13

Where South Carolina sits

The same service costs 3.4 times more in Alaska than in Delaware. Every bar is a state, most expensive first. Touch or drag across it to read any state, then open that state for its carriers and full range.

South Carolina· 42nd of 51

$263

AK $741DE $219

Median negotiated rate in each state, from every insurer that publishes one. States where no insurer publishes a rate for this service are not shown.