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Genetic Test for Changes in a Single Gene

Missouri rates for HCPCS 81352

A laboratory test that examines DNA from a blood or tissue sample to look for changes in one specific gene. The result is used to help confirm a diagnosis, assess risk, or guide treatment decisions, and is normally interpreted alongside personal and family medical history.

Rates data updated July 2026.

How much does Genetic Test for Changes in a Single Gene cost?

$331

Typical negotiated rate. In Missouri, July 2026.

Insurers have agreed to pay about $331 for this service. The price depends on where it is billed: about $288 from a physician practice, and about $427 from a hospital or other facility. The two figures are alternatives, not parts of one bill.

These are rates insurers have negotiated with providers, not the amount a patient is billed. What you owe depends on your plan's deductible and coinsurance. Based on rates published by 6 insurance carriers under federal price transparency rules.

Where it's billed changes the price

Billed byTypicalRange
Physician practiceA doctor's office, clinic or independent provider$288$158 to $389
FacilityA hospital or hospital-owned outpatient department$427$331 to $575

How much rates vary

Facilitymedian $427 · 10th to 90th $288 to $759Professionalmedian $288 · 10th to 90th $132 to $631
$200$500$1Kfacility $427professional $288

Distribution of negotiated rates across all payers (price axis is log-scale). Each curve is scaled to its own total: facility and professional rates are different services, shown together to compare where they cluster. Need provider-level prices or 24+ months of history? Contact us.

Rates by insurance carrier

Insurance Carrier
Aetna
Setting
Facility
Modifier
Global
Typical Low
$288.40
Median
$457.09
Typical High
$758.58
Aetna
Setting
Professional
Modifier
Global
Typical Low
$281.84
Median
$288.40
Typical High
$676.08
Anthem BCBS
Setting
Facility
Modifier
Global
Typical Low
$331.13
Median
$331.13
Typical High
$1,148.15
Anthem BCBS
Setting
Professional
Modifier
Global
Typical Low
$131.83
Median
$134.90
Typical High
$588.84
BCBS
Setting
Professional
Modifier
Global
Typical Low
$229.09
Median
$331.13
Typical High
$371.54
Cigna
Setting
Facility
Modifier
Global
Typical Low
$467.74
Median
$691.83
Typical High
$1,698.24
Cigna
Setting
Professional
Modifier
Global
Typical Low
$144.54
Median
$173.78
Typical High
$457.09
Medica
Setting
Facility
Modifier
Global
Typical Low
$281.84
Median
$398.11
Typical High
$1,548.82
Medica
Setting
Professional
Modifier
Global
Typical Low
$138.04
Median
$199.53
Typical High
$1,659.59
United
Setting
Facility
Modifier
Global
Typical Low
$138.04
Median
$331.13
Typical High
$398.11
United
Setting
Professional
Modifier
Global
Typical Low
$138.04
Median
$199.53
Typical High
$446.68

Where Missouri sits

The same service costs 3.4 times more in Alaska than in Delaware. Every bar is a state, most expensive first. Touch or drag across it to read any state, then open that state for its carriers and full range.

Missouri· 21st of 51

$331

AK $741DE $219

Median negotiated rate in each state, from every insurer that publishes one. States where no insurer publishes a rate for this service are not shown.