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Genetic Test for Changes in a Single Gene

Missouri rates for HCPCS 81352

A laboratory test that examines DNA from a blood or tissue sample to look for changes in one specific gene. The result is used to help confirm a diagnosis, assess risk, or guide treatment decisions, and is normally interpreted alongside personal and family medical history.

Rates data updated October 2026.

How much does Genetic Test for Changes in a Single Gene cost?

$324

Typical negotiated rate. In Missouri, October 2026.

Insurers have agreed to pay about $324 for this service. The price depends on where it is billed: about $316 from a physician practice, and about $575 from a hospital or other facility.

These are rates insurers have negotiated with providers, not the amount a patient is billed. What you owe depends on your plan's deductible and coinsurance. Based on rates published by 6 insurance carriers under federal price transparency rules.

Prices by location type

Billed byTypicalRange
Physician practiceA doctor's office, clinic or independent provider$316$158 to $525
FacilityA hospital or hospital-owned outpatient department$575$347 to $851

How much rates vary

Facilitymedian $575 · 10th to 90th $295 to $1,549Professionalmedian $316 · 10th to 90th $132 to $851
$200$500$1K$2Kfacility $575professional $316

Distribution of negotiated rates across all payers (price axis is log-scale). Need provider-level prices or 24+ months of history? Contact us.

Rates by insurance carrier

Insurance Carrier
Aetna
Setting
Facility
Modifier
None
Typical Low
$281.84
Median
$426.58
Typical High
$602.56
Aetna
Setting
Professional
Modifier
None
Typical Low
$257.04
Median
$281.84
Typical High
$380.19
Anthem BCBS
Setting
Facility
Modifier
None
Typical Low
$331.13
Median
$331.13
Typical High
$1,513.56
Anthem BCBS
Setting
Professional
Modifier
None
Typical Low
$131.83
Median
$354.81
Typical High
$616.60
BCBS Kansas City
Setting
Professional
Modifier
None
Typical Low
$229.09
Median
$331.13
Typical High
$630.96
Cigna
Setting
Facility
Modifier
None
Typical Low
$457.09
Median
$741.31
Typical High
$2,691.53
Cigna
Setting
Professional
Modifier
None
Typical Low
$144.54
Median
$269.15
Typical High
$436.52
Medica
Setting
Facility
Modifier
None
Typical Low
$295.12
Median
$575.44
Typical High
$1,548.82
Medica
Setting
Professional
Modifier
None
Typical Low
$165.96
Median
$338.84
Typical High
$1,659.59
United
Setting
Facility
Modifier
None
Typical Low
$295.12
Median
$295.12
Typical High
$295.12
United
Setting
Professional
Modifier
None
Typical Low
$138.04
Median
$199.53
Typical High
$446.68
2 more rates with less common billing modifiers

A modifier changes what was billed, for example a reduced or repeated service. Each of these modifiers carries under 10% of the published rates for this code. Modifier combinations, and modifiers with fewer than 30 rates for a carrier, are not listed.

Insurance Carrier
Aetna
Setting
Professional
Modifier
52 · Reduced service
Typical Low
$141.25
Median
$141.25
Typical High
$190.55
Aetna
Setting
Professional
Modifier
53 · Discontinued
Typical Low
$56.23
Median
$56.23
Typical High
$75.86

Where Missouri sits

The same service costs 4.3 times more in Alaska than in Alabama. Every bar is a state, most expensive first. Touch or drag across it to read any state, then open that state for its carriers and full range.

Missouri· 27th of 51

$324

AK $741AL $174

Median negotiated rate in each state, from every insurer that publishes one. States where no insurer publishes a rate for this service are not shown.