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Genetic Test for Changes in a Single Gene

Massachusetts rates for HCPCS 81352

A laboratory test that examines DNA from a blood or tissue sample to look for changes in one specific gene. The result is used to help confirm a diagnosis, assess risk, or guide treatment decisions, and is normally interpreted alongside personal and family medical history.

Rates data updated July 2026.

How much does Genetic Test for Changes in a Single Gene cost?

$331

Typical negotiated rate. In Massachusetts, July 2026.

Insurers have agreed to pay about $331 for this service. The price depends on where it is billed: about $331 from a physician practice, and about $661 from a hospital or other facility. The two figures are alternatives, not parts of one bill.

These are rates insurers have negotiated with providers, not the amount a patient is billed. What you owe depends on your plan's deductible and coinsurance. Based on rates published by 8 insurance carriers under federal price transparency rules.

Where it's billed changes the price

Billed byTypicalRange
Physician practiceA doctor's office, clinic or independent provider$331$245 to $331
FacilityA hospital or hospital-owned outpatient department$661$398 to $851

How much rates vary

Facilitymedian $661 · 10th to 90th $245 to $1,023Professionalmedian $331 · 10th to 90th $200 to $813
$200$500$1K$2K$5Kfacility $661professional $331

Distribution of negotiated rates across all payers (price axis is log-scale). Each curve is scaled to its own total: facility and professional rates are different services, shown together to compare where they cluster. Need provider-level prices or 24+ months of history? Contact us.

Rates by insurance carrier

Insurance Carrier
Aetna
Setting
Facility
Modifier
Global
Typical Low
$229.09
Median
$575.44
Typical High
$977.24
Aetna
Setting
Professional
Modifier
Global
Typical Low
$177.83
Median
$245.47
Typical High
$977.24
AllWays Health Partners
Setting
Facility
Modifier
Global
Typical Low
$245.47
Median
$269.15
Typical High
$794.33
AllWays Health Partners
Setting
Professional
Modifier
Global
Typical Low
$199.53
Median
$199.53
Typical High
$1,659.59
BCBS
Setting
Facility
Modifier
Global
Typical Low
$537.03
Median
$660.69
Typical High
$954.99
BCBS
Setting
Professional
Modifier
Global
Typical Low
$309.03
Median
$309.03
Typical High
$309.03
Cigna
Setting
Facility
Modifier
Global
Typical Low
$218.78
Median
$257.04
Typical High
$524.81
Cigna
Setting
Professional
Modifier
Global
Typical Low
$186.21
Median
$354.81
Typical High
$707.95
Fallon Health
Setting
Facility
Modifier
Global
Typical Low
$83.18
Median
$3,630.78
Typical High
$9,772.37
Fallon Health
Setting
Professional
Modifier
Global
Typical Low
$245.47
Median
$478.63
Typical High
$562.34
Harvard Pilgrim
Setting
Professional
Modifier
Global
Typical Low
$331.13
Median
$331.13
Typical High
$549.54
Mass General Brigham
Setting
Facility
Modifier
Global
Typical Low
$245.47
Median
$269.15
Typical High
$794.33
Mass General Brigham
Setting
Professional
Modifier
Global
Typical Low
$199.53
Median
$199.53
Typical High
$1,659.59
United
Setting
Facility
Modifier
Global
Typical Low
$199.53
Median
$331.13
Typical High
$398.11
United
Setting
Professional
Modifier
Global
Typical Low
$199.53
Median
$331.13
Typical High
$758.58

Where Massachusetts sits

The same service costs 3.4 times more in Alaska than in Delaware. Every bar is a state, most expensive first. Touch or drag across it to read any state, then open that state for its carriers and full range.

Massachusetts· 18th of 51

$331

AK $741DE $219

Median negotiated rate in each state, from every insurer that publishes one. States where no insurer publishes a rate for this service are not shown.