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Genetic Test for Changes in a Single Gene

Illinois rates for HCPCS 81352

A laboratory test that examines DNA from a blood or tissue sample to look for changes in one specific gene. The result is used to help confirm a diagnosis, assess risk, or guide treatment decisions, and is normally interpreted alongside personal and family medical history.

Rates data updated July 2026.

How much does Genetic Test for Changes in a Single Gene cost?

$269

Typical negotiated rate. In Illinois, July 2026.

Insurers have agreed to pay about $269 for this service. The price depends on where it is billed: about $251 from a physician practice, and about $501 from a hospital or other facility. The two figures are alternatives, not parts of one bill.

These are rates insurers have negotiated with providers, not the amount a patient is billed. What you owe depends on your plan's deductible and coinsurance. Based on rates published by 5 insurance carriers under federal price transparency rules.

Where it's billed changes the price

Billed byTypicalRange
Physician practiceA doctor's office, clinic or independent provider$251$182 to $282
FacilityA hospital or hospital-owned outpatient department$501$339 to $661

How much rates vary

Facilitymedian $501 · 10th to 90th $269 to $851Professionalmedian $251 · 10th to 90th $3 to $501
$10$100$1Kfacility $501professional $251

Distribution of negotiated rates across all payers (price axis is log-scale). Each curve is scaled to its own total: facility and professional rates are different services, shown together to compare where they cluster. Need provider-level prices or 24+ months of history? Contact us.

Rates by insurance carrier

Insurance Carrier
Aetna
Setting
Facility
Modifier
Global
Typical Low
$269.15
Median
$501.19
Typical High
$676.08
Aetna
Setting
Professional
Modifier
Global
Typical Low
$245.47
Median
$281.84
Typical High
$562.34
BCBS
Setting
Facility
Modifier
Global
Typical Low
$398.11
Median
$524.81
Typical High
$4,265.80
BCBS
Setting
Professional
Modifier
Global
Typical Low
$3.47
Median
$229.09
Typical High
$251.19
Cigna
Setting
Facility
Modifier
Global
Typical Low
$389.05
Median
$758.58
Typical High
$1,513.56
Cigna
Setting
Professional
Modifier
Global
Typical Low
$151.36
Median
$398.11
Typical High
$562.34
Hally Health
Setting
Professional
Modifier
Global
Typical Low
$346.74
Median
$575.44
Typical High
$1,230.27
Hally Health
Setting
Facility
Modifier
Global
Typical Low
$100.00
Median
$100.00
Typical High
$100.00
Hally Health
Setting
Professional
Modifier
Global
Typical Low
$426.58
Median
$426.58
Typical High
$426.58
United
Setting
Facility
Modifier
Global
Typical Low
$331.13
Median
$331.13
Typical High
$660.69
United
Setting
Professional
Modifier
Global
Typical Low
$138.04
Median
$199.53
Typical High
$331.13

Where Illinois sits

The same service costs 3.4 times more in Alaska than in Delaware. Every bar is a state, most expensive first. Touch or drag across it to read any state, then open that state for its carriers and full range.

Illinois· 41st of 51

$269

AK $741DE $219

Median negotiated rate in each state, from every insurer that publishes one. States where no insurer publishes a rate for this service are not shown.