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Genetic Test for Changes in a Single Gene

Virginia rates for HCPCS 81351

A laboratory test that examines DNA from a blood or tissue sample to look for changes in one specific gene. The result is used to help confirm a diagnosis, assess risk, or guide treatment decisions, and is normally interpreted alongside personal and family medical history.

Rates data updated July 2026.

How much does Genetic Test for Changes in a Single Gene cost?

$550

Typical negotiated rate. In Virginia, July 2026.

Insurers have agreed to pay about $550 for this service. The price depends on where it is billed: about $479 from a physician practice, and about $676 from a hospital or other facility. The two figures are alternatives, not parts of one bill.

These are rates insurers have negotiated with providers, not the amount a patient is billed. What you owe depends on your plan's deductible and coinsurance. Based on rates published by 8 insurance carriers under federal price transparency rules.

Where it's billed changes the price

Billed byTypicalRange
Physician practiceA doctor's office, clinic or independent provider$479$288 to $550
FacilityA hospital or hospital-owned outpatient department$676$646 to $1,349

How much rates vary

Facilitymedian $676 · 10th to 90th $550 to $2,344Professionalmedian $479 · 10th to 90th $257 to $1,047
$500$1K$2K$5K$10Kfacility $676professional $479

Distribution of negotiated rates across all payers (price axis is log-scale). Each curve is scaled to its own total: facility and professional rates are different services, shown together to compare where they cluster. Need provider-level prices or 24+ months of history? Contact us.

Rates by insurance carrier

Insurance Carrier
Aetna
Setting
Facility
Modifier
Global
Typical Low
$478.63
Median
$1,230.27
Typical High
$1,584.89
Aetna
Setting
Professional
Modifier
Global
Typical Low
$478.63
Median
$549.54
Typical High
$1,230.27
Anthem BCBS
Setting
Facility
Modifier
Global
Typical Low
$645.65
Median
$645.65
Typical High
$2,570.40
Anthem BCBS
Setting
Professional
Modifier
Global
Typical Low
$257.04
Median
$257.04
Typical High
$426.58
CareFirst
Setting
Professional
Modifier
Global
Typical Low
$489.78
Median
$549.54
Typical High
$616.60
Cigna
Setting
Facility
Modifier
Global
Typical Low
$660.69
Median
$1,258.93
Typical High
$3,311.31
Cigna
Setting
Professional
Modifier
Global
Typical Low
$316.23
Median
$398.11
Typical High
$1,023.29
Kaiser Permanente
Setting
Professional
Modifier
Global
Typical Low
$645.65
Median
$707.95
Typical High
$891.25
Medcost
Setting
Facility
Modifier
Global
Typical Low
$478.63
Median
$645.65
Typical High
$1,096.48
Medcost
Setting
Professional
Modifier
Global
Typical Low
$416.87
Median
$416.87
Typical High
$1,348.96
Sentara
Setting
Facility
Modifier
Global
Typical Low
$549.54
Median
$758.58
Typical High
$10,000.00
Sentara
Setting
Professional
Modifier
Global
Typical Low
$549.54
Median
$776.25
Typical High
$10,000.00
United
Setting
Facility
Modifier
Global
Typical Low
$389.05
Median
$645.65
Typical High
$776.25
United
Setting
Professional
Modifier
Global
Typical Low
$269.15
Median
$323.59
Typical High
$741.31

Where Virginia sits

The same service costs 3.4 times more in Alaska than in Delaware. Every bar is a state, most expensive first. Touch or drag across it to read any state, then open that state for its carriers and full range.

Virginia· 37th of 51

$550

AK $1,445DE $427

Median negotiated rate in each state, from every insurer that publishes one. States where no insurer publishes a rate for this service are not shown.