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Genetic Test for Changes in a Single Gene

South Carolina rates for HCPCS 81351

A laboratory test that examines DNA from a blood or tissue sample to look for changes in one specific gene. The result is used to help confirm a diagnosis, assess risk, or guide treatment decisions, and is normally interpreted alongside personal and family medical history.

Rates data updated July 2026.

How much does Genetic Test for Changes in a Single Gene cost?

$513

Typical negotiated rate. In South Carolina, July 2026.

Insurers have agreed to pay about $513 for this service. The price depends on where it is billed: about $501 from a physician practice, and about $1,585 from a hospital or other facility. The two figures are alternatives, not parts of one bill.

These are rates insurers have negotiated with providers, not the amount a patient is billed. What you owe depends on your plan's deductible and coinsurance. Based on rates published by 5 insurance carriers under federal price transparency rules.

Where it's billed changes the price

Billed byTypicalRange
Physician practiceA doctor's office, clinic or independent provider$501$501 to $525
FacilityA hospital or hospital-owned outpatient department$1,585$513 to $2,042

How much rates vary

Facilitymedian $1,585 · 10th to 90th $501 to $3,020Professionalmedian $501 · 10th to 90th $309 to $676
$500$1K$2Kfacility $1,585professional $501

Distribution of negotiated rates across all payers (price axis is log-scale). Each curve is scaled to its own total: facility and professional rates are different services, shown together to compare where they cluster. Need provider-level prices or 24+ months of history? Contact us.

Rates by insurance carrier

Insurance Carrier
Aetna
Setting
Facility
Modifier
Global
Typical Low
$501.19
Median
$1,584.89
Typical High
$3,019.95
Aetna
Setting
Professional
Modifier
Global
Typical Low
$501.19
Median
$501.19
Typical High
$602.56
BCBS
Setting
Professional
Modifier
Global
Typical Low
$229.09
Median
$346.74
Typical High
$794.33
Cigna
Setting
Facility
Modifier
Global
Typical Low
$1,202.26
Median
$2,089.30
Typical High
$3,630.78
Cigna
Setting
Professional
Modifier
Global
Typical Low
$288.40
Median
$316.23
Typical High
$776.25
Medcost
Setting
Facility
Modifier
Global
Typical Low
$501.19
Median
$575.44
Typical High
$851.14
United
Setting
Facility
Modifier
Global
Typical Low
$575.44
Median
$645.65
Typical High
$776.25
United
Setting
Professional
Modifier
Global
Typical Low
$269.15
Median
$389.05
Typical High
$645.65

Where South Carolina sits

The same service costs 3.4 times more in Alaska than in Delaware. Every bar is a state, most expensive first. Touch or drag across it to read any state, then open that state for its carriers and full range.

South Carolina· 43rd of 51

$513

AK $1,445DE $427

Median negotiated rate in each state, from every insurer that publishes one. States where no insurer publishes a rate for this service are not shown.