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Genetic Test for Changes in a Single Gene

Rhode Island rates for HCPCS 81351

A laboratory test that examines DNA from a blood or tissue sample to look for changes in one specific gene. The result is used to help confirm a diagnosis, assess risk, or guide treatment decisions, and is normally interpreted alongside personal and family medical history.

Rates data updated July 2026.

How much does Genetic Test for Changes in a Single Gene cost?

$479

Typical negotiated rate. In Rhode Island, July 2026.

Insurers have agreed to pay about $479 for this service. The price depends on where it is billed: about $479 from a physician practice, and about $813 from a hospital or other facility. The two figures are alternatives, not parts of one bill.

These are rates insurers have negotiated with providers, not the amount a patient is billed. What you owe depends on your plan's deductible and coinsurance. Based on rates published by 4 insurance carriers under federal price transparency rules.

Where it's billed changes the price

Billed byTypicalRange
Physician practiceA doctor's office, clinic or independent provider$479$447 to $479
FacilityA hospital or hospital-owned outpatient department$813$741 to $2,884

How much rates vary

Facilitymedian $813 · 10th to 90th $646 to $2,884Professionalmedian $479 · 10th to 90th $389 to $646
$500$1K$2Kfacility $813professional $479

Distribution of negotiated rates across all payers (price axis is log-scale). Each curve is scaled to its own total: facility and professional rates are different services, shown together to compare where they cluster. Small sample; interpret with caution. Need provider-level prices or 24+ months of history? Contact us.

Rates by insurance carrier

Insurance Carrier
Aetna
Setting
Facility
Modifier
Global
Typical Low
$1,862.09
Median
$2,884.03
Typical High
$2,884.03
Aetna
Setting
Professional
Modifier
Global
Typical Low
$446.68
Median
$446.68
Typical High
$478.63
BCBS
Setting
Facility
Modifier
Global
Typical Low
$575.44
Median
$741.31
Typical High
$812.83
BCBS
Setting
Professional
Modifier
Global
Typical Low
$478.63
Median
$478.63
Typical High
$707.95
Cigna
Setting
Facility
Modifier
Global
Typical Low
$1,949.84
Median
$1,949.84
Typical High
$1,949.84
Cigna
Setting
Professional
Modifier
Global
Typical Low
$331.13
Median
$371.54
Typical High
$1,023.29
United
Setting
Facility
Modifier
Global
Typical Low
$776.25
Median
$776.25
Typical High
$891.25
United
Setting
Professional
Modifier
Global
Typical Low
$269.15
Median
$389.05
Typical High
$933.25

Where Rhode Island sits

The same service costs 3.4 times more in Alaska than in Delaware. Every bar is a state, most expensive first. Touch or drag across it to read any state, then open that state for its carriers and full range.

Rhode Island· 47th of 51

$479

AK $1,445DE $427

Median negotiated rate in each state, from every insurer that publishes one. States where no insurer publishes a rate for this service are not shown.