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Genetic Test for Changes in a Single Gene

Oklahoma rates for HCPCS 81351

A laboratory test that examines DNA from a blood or tissue sample to look for changes in one specific gene. The result is used to help confirm a diagnosis, assess risk, or guide treatment decisions, and is normally interpreted alongside personal and family medical history.

Rates data updated July 2026.

How much does Genetic Test for Changes in a Single Gene cost?

$813

Typical negotiated rate. In Oklahoma, July 2026.

Insurers have agreed to pay about $813 for this service. The price depends on where it is billed: about $479 from a physician practice, and about $1,096 from a hospital or other facility. The two figures are alternatives, not parts of one bill.

These are rates insurers have negotiated with providers, not the amount a patient is billed. What you owe depends on your plan's deductible and coinsurance. Based on rates published by 5 insurance carriers under federal price transparency rules.

Where it's billed changes the price

Billed byTypicalRange
Physician practiceA doctor's office, clinic or independent provider$479$389 to $646
FacilityA hospital or hospital-owned outpatient department$1,096$646 to $1,514

How much rates vary

Facilitymedian $1,096 · 10th to 90th $479 to $1,778Professionalmedian $479 · 10th to 90th $269 to $813
$500$1K$2Kfacility $1,096professional $479

Distribution of negotiated rates across all payers (price axis is log-scale). Each curve is scaled to its own total: facility and professional rates are different services, shown together to compare where they cluster. Need provider-level prices or 24+ months of history? Contact us.

Rates by insurance carrier

Insurance Carrier
Aetna
Setting
Facility
Modifier
Global
Typical Low
$478.63
Median
$645.65
Typical High
$1,621.81
Aetna
Setting
Professional
Modifier
Global
Typical Low
$478.63
Median
$478.63
Typical High
$812.83
BCBS
Setting
Facility
Modifier
Global
Typical Low
$891.25
Median
$1,230.27
Typical High
$1,778.28
BCBS
Setting
Professional
Modifier
Global
Typical Low
$616.60
Median
$616.60
Typical High
$616.60
Cigna
Setting
Facility
Modifier
Global
Typical Low
$562.34
Median
$1,698.24
Typical High
$1,737.80
Cigna
Setting
Professional
Modifier
Global
Typical Low
$269.15
Median
$288.40
Typical High
$933.25
Medica
Setting
Facility
Modifier
Global
Typical Low
$478.63
Median
$645.65
Typical High
$1,122.02
Medica
Setting
Professional
Modifier
Global
Typical Low
$269.15
Median
$269.15
Typical High
$954.99
United
Setting
Facility
Modifier
Global
Typical Low
$229.09
Median
$645.65
Typical High
$776.25
United
Setting
Professional
Modifier
Global
Typical Low
$269.15
Median
$269.15
Typical High
$426.58

Where Oklahoma sits

The same service costs 3.4 times more in Alaska than in Delaware. Every bar is a state, most expensive first. Touch or drag across it to read any state, then open that state for its carriers and full range.

Oklahoma· 5th of 51

$813

AK $1,445DE $427

Median negotiated rate in each state, from every insurer that publishes one. States where no insurer publishes a rate for this service are not shown.