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Genetic Test for Changes in a Single Gene

Ohio rates for HCPCS 81351

A laboratory test that examines DNA from a blood or tissue sample to look for changes in one specific gene. The result is used to help confirm a diagnosis, assess risk, or guide treatment decisions, and is normally interpreted alongside personal and family medical history.

Rates data updated July 2026.

How much does Genetic Test for Changes in a Single Gene cost?

$525

Typical negotiated rate. In Ohio, July 2026.

Insurers have agreed to pay about $525 for this service. The price depends on where it is billed: about $513 from a physician practice, and about $776 from a hospital or other facility. The two figures are alternatives, not parts of one bill.

These are rates insurers have negotiated with providers, not the amount a patient is billed. What you owe depends on your plan's deductible and coinsurance. Based on rates published by 8 insurance carriers under federal price transparency rules.

Where it's billed changes the price

Billed byTypicalRange
Physician practiceA doctor's office, clinic or independent provider$513$331 to $603
FacilityA hospital or hospital-owned outpatient department$776$646 to $1,148

How much rates vary

Facilitymedian $776 · 10th to 90th $513 to $1,549Professionalmedian $513 · 10th to 90th $257 to $977
$500$1K$2Kfacility $776professional $513

Distribution of negotiated rates across all payers (price axis is log-scale). Each curve is scaled to its own total: facility and professional rates are different services, shown together to compare where they cluster. Need provider-level prices or 24+ months of history? Contact us.

Rates by insurance carrier

Insurance Carrier
Aetna
Setting
Facility
Modifier
Global
Typical Low
$512.86
Median
$977.24
Typical High
$1,548.82
Aetna
Setting
Professional
Modifier
Global
Typical Low
$512.86
Median
$512.86
Typical High
$1,096.48
Anthem BCBS
Setting
Facility
Modifier
Global
Typical Low
$588.84
Median
$676.08
Typical High
$1,174.90
Anthem BCBS
Setting
Professional
Modifier
Global
Typical Low
$257.04
Median
$331.13
Typical High
$831.76
CareSource
Setting
Facility
Modifier
Global
Typical Low
$512.86
Median
$741.31
Typical High
$891.25
CareSource
Setting
Professional
Modifier
Global
Typical Low
$645.65
Median
$645.65
Typical High
$870.96
Cigna
Setting
Facility
Modifier
Global
Typical Low
$630.96
Median
$831.76
Typical High
$3,235.94
Cigna
Setting
Professional
Modifier
Global
Typical Low
$295.12
Median
$363.08
Typical High
$1,288.25
Medical Mutual of Ohio
Setting
Facility
Modifier
Global
Typical Low
$691.83
Median
$851.14
Typical High
$3,548.13
Medical Mutual of Ohio
Setting
Professional
Modifier
Global
Typical Low
$295.12
Median
$363.08
Typical High
$1,230.27
Molina
Setting
Professional
Modifier
Global
Typical Low
$60.26
Median
$524.81
Typical High
$676.08
SummaCare
Setting
Professional
Modifier
Global
Typical Low
$549.54
Median
$776.25
Typical High
$1,479.11
United
Setting
Facility
Modifier
Global
Typical Low
$389.05
Median
$645.65
Typical High
$954.99
United
Setting
Professional
Modifier
Global
Typical Low
$269.15
Median
$389.05
Typical High
$891.25

Where Ohio sits

The same service costs 3.4 times more in Alaska than in Delaware. Every bar is a state, most expensive first. Touch or drag across it to read any state, then open that state for its carriers and full range.

Ohio· 42nd of 51

$525

AK $1,445DE $427

Median negotiated rate in each state, from every insurer that publishes one. States where no insurer publishes a rate for this service are not shown.