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Genetic Test for Changes in a Single Gene

Michigan rates for HCPCS 81351

A laboratory test that examines DNA from a blood or tissue sample to look for changes in one specific gene. The result is used to help confirm a diagnosis, assess risk, or guide treatment decisions, and is normally interpreted alongside personal and family medical history.

Rates data updated July 2026.

How much does Genetic Test for Changes in a Single Gene cost?

$617

Typical negotiated rate. In Michigan, July 2026.

Insurers have agreed to pay about $617 for this service. The price depends on where it is billed: about $525 from a physician practice, and about $646 from a hospital or other facility. The two figures are alternatives, not parts of one bill.

These are rates insurers have negotiated with providers, not the amount a patient is billed. What you owe depends on your plan's deductible and coinsurance. Based on rates published by 7 insurance carriers under federal price transparency rules.

Where it's billed changes the price

Billed byTypicalRange
Physician practiceA doctor's office, clinic or independent provider$525$479 to $617
FacilityA hospital or hospital-owned outpatient department$646$617 to $1,122

How much rates vary

Facilitymedian $646 · 10th to 90th $603 to $5,012Professionalmedian $525 · 10th to 90th $347 to $759
$500$1K$2K$5Kfacility $646professional $525

Distribution of negotiated rates across all payers (price axis is log-scale). Each curve is scaled to its own total: facility and professional rates are different services, shown together to compare where they cluster. Need provider-level prices or 24+ months of history? Contact us.

Rates by insurance carrier

Insurance Carrier
Aetna
Setting
Facility
Modifier
Global
Typical Low
$616.60
Median
$616.60
Typical High
$5,011.87
Aetna
Setting
Professional
Modifier
Global
Typical Low
$346.74
Median
$616.60
Typical High
$758.58
BCBS
Setting
Facility
Modifier
Global
Typical Low
$478.63
Median
$707.95
Typical High
$1,258.93
BCBS
Setting
Professional
Modifier
Global
Typical Low
$457.09
Median
$478.63
Typical High
$478.63
CareSource
Setting
Facility
Modifier
Global
Typical Low
$645.65
Median
$645.65
Typical High
$645.65
CareSource
Setting
Professional
Modifier
Global
Typical Low
$645.65
Median
$707.95
Typical High
$870.96
Cigna
Setting
Professional
Modifier
Global
Typical Low
$295.12
Median
$363.08
Typical High
$891.25
Health Alliance Plan
Setting
Facility
Modifier
Global
Typical Low
$602.56
Median
$660.69
Typical High
$1,548.82
Health Alliance Plan
Setting
Professional
Modifier
Global
Typical Low
$512.86
Median
$645.65
Typical High
$870.96
Priority Health
Setting
Professional
Modifier
Global
Typical Low
$741.31
Median
$741.31
Typical High
$776.25
United
Setting
Facility
Modifier
Global
Typical Low
$389.05
Median
$645.65
Typical High
$776.25
United
Setting
Professional
Modifier
Global
Typical Low
$269.15
Median
$389.05
Typical High
$645.65

Where Michigan sits

The same service costs 3.4 times more in Alaska than in Delaware. Every bar is a state, most expensive first. Touch or drag across it to read any state, then open that state for its carriers and full range.

Michigan· 30th of 51

$617

AK $1,445DE $427

Median negotiated rate in each state, from every insurer that publishes one. States where no insurer publishes a rate for this service are not shown.