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Genetic Test for Changes in a Single Gene

Maryland rates for HCPCS 81351

A laboratory test that examines DNA from a blood or tissue sample to look for changes in one specific gene. The result is used to help confirm a diagnosis, assess risk, or guide treatment decisions, and is normally interpreted alongside personal and family medical history.

Rates data updated July 2026.

How much does Genetic Test for Changes in a Single Gene cost?

$479

Typical negotiated rate. In Maryland, July 2026.

Insurers have agreed to pay about $479 for this service. Most negotiated rates run $417 to $550.

These are rates insurers have negotiated with providers, not the amount a patient is billed. What you owe depends on your plan's deductible and coinsurance. Based on rates published by 6 insurance carriers under federal price transparency rules.

How much rates vary

Facilitymedian $269 · 10th to 90th $269 to $490Professionalmedian $479 · 10th to 90th $288 to $776
$500$1K$2Kfacility $269professional $479

Distribution of negotiated rates across all payers (price axis is log-scale). Each curve is scaled to its own total: facility and professional rates are different services, shown together to compare where they cluster. Small sample; interpret with caution. Need provider-level prices or 24+ months of history? Contact us.

Rates by insurance carrier

Insurance Carrier
Aetna
Setting
Professional
Modifier
Global
Typical Low
$416.87
Median
$478.63
Typical High
$602.56
CareFirst
Setting
Professional
Modifier
Global
Typical Low
$457.09
Median
$457.09
Typical High
$575.44
Cigna
Setting
Professional
Modifier
Global
Typical Low
$346.74
Median
$398.11
Typical High
$1,122.02
Kaiser Permanente
Setting
Professional
Modifier
Global
Typical Low
$645.65
Median
$776.25
Typical High
$954.99
United
Setting
Facility
Modifier
Global
Typical Low
$269.15
Median
$269.15
Typical High
$489.78
United
Setting
Professional
Modifier
Global
Typical Low
$269.15
Median
$288.40
Typical High
$562.34
Wellpoint
Setting
Professional
Modifier
Global
Typical Low
$323.59
Median
$323.59
Typical High
$323.59

Where Maryland sits

The same service costs 3.4 times more in Alaska than in Delaware. Every bar is a state, most expensive first. Touch or drag across it to read any state, then open that state for its carriers and full range.

Maryland· 48th of 51

$479

AK $1,445DE $427

Median negotiated rate in each state, from every insurer that publishes one. States where no insurer publishes a rate for this service are not shown.