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Genetic Test for Changes in a Single Gene

Connecticut rates for HCPCS 81351

A laboratory test that examines DNA from a blood or tissue sample to look for changes in one specific gene. The result is used to help confirm a diagnosis, assess risk, or guide treatment decisions, and is normally interpreted alongside personal and family medical history.

Rates data updated July 2026.

How much does Genetic Test for Changes in a Single Gene cost?

$646

Typical negotiated rate. In Connecticut, July 2026.

Insurers have agreed to pay about $646 for this service. The price depends on where it is billed: about $427 from a physician practice, and about $912 from a hospital or other facility. The two figures are alternatives, not parts of one bill.

These are rates insurers have negotiated with providers, not the amount a patient is billed. What you owe depends on your plan's deductible and coinsurance. Based on rates published by 5 insurance carriers under federal price transparency rules.

Where it's billed changes the price

Billed byTypicalRange
Physician practiceA doctor's office, clinic or independent provider$427$389 to $851
FacilityA hospital or hospital-owned outpatient department$912$646 to $1,349

How much rates vary

Facilitymedian $912 · 10th to 90th $646 to $1,738Professionalmedian $427 · 10th to 90th $339 to $1,445
$500$1K$2Kfacility $912professional $427

Distribution of negotiated rates across all payers (price axis is log-scale). Each curve is scaled to its own total: facility and professional rates are different services, shown together to compare where they cluster. Need provider-level prices or 24+ months of history? Contact us.

Rates by insurance carrier

Insurance Carrier
Aetna
Setting
Facility
Modifier
Global
Typical Low
$645.65
Median
$870.96
Typical High
$1,698.24
Aetna
Setting
Professional
Modifier
Global
Typical Low
$338.84
Median
$426.58
Typical High
$1,445.44
Anthem BCBS
Setting
Facility
Modifier
Global
Typical Low
$562.34
Median
$1,000.00
Typical High
$1,737.80
Anthem BCBS
Setting
Professional
Modifier
Global
Typical Low
$257.04
Median
$630.96
Typical High
$1,445.44
Cigna
Setting
Facility
Modifier
Global
Typical Low
$1,023.29
Median
$2,137.96
Typical High
$3,235.94
Cigna
Setting
Professional
Modifier
Global
Typical Low
$354.81
Median
$707.95
Typical High
$1,318.26
ConnectiCare
Setting
Professional
Modifier
Global
Typical Low
$630.96
Median
$676.08
Typical High
$1,230.27
United
Setting
Facility
Modifier
Global
Typical Low
$645.65
Median
$645.65
Typical High
$645.65
United
Setting
Professional
Modifier
Global
Typical Low
$288.40
Median
$436.52
Typical High
$1,047.13

Where Connecticut sits

The same service costs 3.4 times more in Alaska than in Delaware. Every bar is a state, most expensive first. Touch or drag across it to read any state, then open that state for its carriers and full range.

Connecticut· 17th of 51

$646

AK $1,445DE $427

Median negotiated rate in each state, from every insurer that publishes one. States where no insurer publishes a rate for this service are not shown.