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Gene Test Guiding Chemotherapy Dosing

Missouri rates for HCPCS 81346

A laboratory test that examines one particular gene in a blood sample for specific known variations that change how the body handles a chemotherapy medicine. People carrying certain versions clear the medicine faster or slower than usual, which alters how much benefit and how much side effect a standard dose produces. The result helps the treating team set the dose or choose between medicines; it is not used to diagnose a condition.

Rates data updated July 2026.

How much does Gene Test Guiding Chemotherapy Dosing cost?

$174

Typical negotiated rate. In Missouri, July 2026.

Insurers have agreed to pay about $174 for this service. The price depends on where it is billed: about $151 from a physician practice, and about $229 from a hospital or other facility. The two figures are alternatives, not parts of one bill.

These are rates insurers have negotiated with providers, not the amount a patient is billed. What you owe depends on your plan's deductible and coinsurance. Based on rates published by 6 insurance carriers under federal price transparency rules.

Where it's billed changes the price

Billed byTypicalRange
Physician practiceA doctor's office, clinic or independent provider$151$105 to $204
FacilityA hospital or hospital-owned outpatient department$229$174 to $302

How much rates vary

Facilitymedian $229 · 10th to 90th $170 to $407Professionalmedian $151 · 10th to 90th $69 to $339
$10.0$20.0$50.0$100.0$200.0$500.0$1.0Kfacility $229professional $151

Distribution of negotiated rates across all payers (price axis is log-scale). Each curve is scaled to its own total: facility and professional rates are different services, shown together to compare where they cluster. Need provider-level prices or 24+ months of history? Contact us.

Rates by insurance carrier

Insurance Carrier
Aetna
Setting
Facility
Modifier
Global
Typical Low
$169.82
Median
$295.12
Typical High
$407.38
Aetna
Setting
Professional
Modifier
Global
Typical Low
$147.91
Median
$165.96
Typical High
$354.81
Anthem BCBS
Setting
Facility
Modifier
Global
Typical Low
$173.78
Median
$173.78
Typical High
$616.60
Anthem BCBS
Setting
Professional
Modifier
Global
Typical Low
$69.18
Median
$104.71
Typical High
$302.00
BCBS
Setting
Facility
Modifier
Global
Typical Low
$245.47
Median
$257.04
Typical High
$457.09
BCBS
Setting
Professional
Modifier
Global
Typical Low
$123.03
Median
$173.78
Typical High
$194.98
Cigna
Setting
Facility
Modifier
Global
Typical Low
$177.83
Median
$338.84
Typical High
$562.34
Cigna
Setting
Professional
Modifier
Global
Typical Low
$74.13
Median
$89.13
Typical High
$234.42
Medica
Setting
Facility
Modifier
Global
Typical Low
$151.36
Median
$208.93
Typical High
$831.76
Medica
Setting
Professional
Modifier
Global
Typical Low
$74.13
Median
$104.71
Typical High
$870.96
United
Setting
Facility
Modifier
Global
Typical Low
$74.13
Median
$173.78
Typical High
$208.93
United
Setting
Professional
Modifier
Global
Typical Low
$74.13
Median
$104.71
Typical High
$234.42

Where Missouri sits

The same service costs 3.3 times more in Alaska than in Delaware. Every bar is a state, most expensive first. Pick one to see its carriers and full range.

Missouri $174 · 25th of 51
AK $389DE $117

Median negotiated rate in each state, from every insurer that publishes one. States where no insurer publishes a rate for this service are not shown.