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Gene Test Guiding Chemotherapy Dosing

Maryland rates for HCPCS 81346

A laboratory test that examines one particular gene in a blood sample for specific known variations that change how the body handles a chemotherapy medicine. People carrying certain versions clear the medicine faster or slower than usual, which alters how much benefit and how much side effect a standard dose produces. The result helps the treating team set the dose or choose between medicines; it is not used to diagnose a condition.

Rates data updated October 2026.

How much does Gene Test Guiding Chemotherapy Dosing cost?

$129

Typical negotiated rate. In Maryland, October 2026.

Insurers have agreed to pay about $129 for this service. Most negotiated rates run $107 to $141.

These are rates insurers have negotiated with providers, not the amount a patient is billed. What you owe depends on your plan's deductible and coinsurance. Based on rates published by 6 insurance carriers under federal price transparency rules.

How much rates vary

Professionalmedian $129 · 10th to 90th $79 to $174
$100$200$500professional $129

Distribution of negotiated rates across all payers (price axis is log-scale). Need provider-level prices or 24+ months of history? Contact us.

Rates by insurance carrier

Insurance Carrier
Aetna
Setting
Professional
Modifier
None
Typical Low
$128.82
Median
$131.83
Typical High
$144.54
CareFirst
Setting
Professional
Modifier
None
Typical Low
$125.89
Median
$141.25
Typical High
$141.25
Cigna
Setting
Professional
Modifier
None
Typical Low
$91.20
Median
$123.03
Typical High
$501.19
Kaiser Permanente
Setting
Professional
Modifier
None
Typical Low
$173.78
Median
$208.93
Typical High
$263.03
United
Setting
Professional
Modifier
None
Typical Low
$74.13
Median
$87.10
Typical High
$151.36
Wellpoint
Setting
Professional
Modifier
None
Typical Low
$87.10
Median
$87.10
Typical High
$141.25
2 more rates with less common billing modifiers

A modifier changes what was billed, for example a reduced or repeated service. Each of these modifiers carries under 10% of the published rates for this code. Modifier combinations, and modifiers with fewer than 30 rates for a carrier, are not listed.

Insurance Carrier
Aetna
Setting
Professional
Modifier
52 · Reduced service
Typical Low
$64.57
Median
$66.07
Typical High
$72.44
Aetna
Setting
Professional
Modifier
53 · Discontinued
Typical Low
$25.70
Median
$26.30
Typical High
$28.84

Where Maryland sits

The same service costs 3.7 times more in Alaska than in Delaware. Every bar is a state, most expensive first. Touch or drag across it to read any state, then open that state for its carriers and full range.

Maryland· 46th of 51

$129

AK $389DE $105

Median negotiated rate in each state, from every insurer that publishes one. States where no insurer publishes a rate for this service are not shown.