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Gene Test Guiding Chemotherapy Dosing

Massachusetts rates for HCPCS 81346

A laboratory test that examines one particular gene in a blood sample for specific known variations that change how the body handles a chemotherapy medicine. People carrying certain versions clear the medicine faster or slower than usual, which alters how much benefit and how much side effect a standard dose produces. The result helps the treating team set the dose or choose between medicines; it is not used to diagnose a condition.

Rates data updated October 2026.

How much does Gene Test Guiding Chemotherapy Dosing cost?

$182

Typical negotiated rate. In Massachusetts, October 2026.

Insurers have agreed to pay about $182 for this service. The price depends on where it is billed: about $174 from a physician practice, and about $251 from a hospital or other facility.

These are rates insurers have negotiated with providers, not the amount a patient is billed. What you owe depends on your plan's deductible and coinsurance. Based on rates published by 9 insurance carriers under federal price transparency rules.

Prices by location type

Billed byTypicalRange
Physician practiceA doctor's office, clinic or independent provider$174$105 to $437
FacilityA hospital or hospital-owned outpatient department$251$182 to $407

How much rates vary

Facilitymedian $251 · 10th to 90th $129 to $562Professionalmedian $174 · 10th to 90th $105 to $871
$100$200$500$1K$2K$5Kfacility $251professional $174

Distribution of negotiated rates across all payers (price axis is log-scale). Need provider-level prices or 24+ months of history? Contact us.

Rates by insurance carrier

Insurance Carrier
Aetna
Setting
Facility
Modifier
None
Typical Low
$123.03
Median
$245.47
Typical High
$549.54
Aetna
Setting
Professional
Modifier
None
Typical Low
$123.03
Median
$123.03
Typical High
$123.03
AllWays Health Partners
Setting
Facility
Modifier
None
Typical Low
$128.82
Median
$199.53
Typical High
$537.03
AllWays Health Partners
Setting
Professional
Modifier
None
Typical Low
$104.71
Median
$354.81
Typical High
$870.96
BCBS Massachusetts
Setting
Facility
Modifier
None
Typical Low
$275.42
Median
$389.05
Typical High
$562.34
BCBS Massachusetts
Setting
Professional
Modifier
None
Typical Low
$162.18
Median
$162.18
Typical High
$162.18
Cigna
Setting
Facility
Modifier
None
Typical Low
$114.82
Median
$138.04
Typical High
$338.84
Cigna
Setting
Professional
Modifier
None
Typical Low
$97.72
Median
$208.93
Typical High
$676.08
Fallon Health
Setting
Facility
Modifier
None
Typical Low
$91.20
Median
$295.12
Typical High
$5,888.44
Fallon Health
Setting
Professional
Modifier
None
Typical Low
$251.19
Median
$251.19
Typical High
$295.12
Harvard Pilgrim
Setting
Professional
Modifier
None
Typical Low
$104.71
Median
$173.78
Typical High
$446.68
Mass General Brigham
Setting
Facility
Modifier
None
Typical Low
$128.82
Median
$199.53
Typical High
$537.03
Mass General Brigham
Setting
Professional
Modifier
None
Typical Low
$104.71
Median
$354.81
Typical High
$870.96
United
Setting
Facility
Modifier
None
Typical Low
$158.49
Median
$173.78
Typical High
$208.93
United
Setting
Professional
Modifier
None
Typical Low
$69.18
Median
$104.71
Typical High
$331.13
Well Sense
Setting
Facility
Modifier
None
Typical Low
$154.88
Median
$213.80
Typical High
$316.23
Well Sense
Setting
Professional
Modifier
None
Typical Low
$131.83
Median
$131.83
Typical High
$154.88
3 more rates with less common billing modifiers

A modifier changes what was billed, for example a reduced or repeated service. Each of these modifiers carries under 10% of the published rates for this code. Modifier combinations, and modifiers with fewer than 30 rates for a carrier, are not listed.

Insurance Carrier
Aetna
Setting
Professional
Modifier
52 · Reduced service
Typical Low
$61.66
Median
$61.66
Typical High
$61.66
Aetna
Setting
Professional
Modifier
53 · Discontinued
Typical Low
$24.55
Median
$24.55
Typical High
$24.55
Fallon Health
Setting
Facility
Modifier
QW · Waived lab test
Typical Low
$173.78
Median
$229.09
Typical High
$269.15

Where Massachusetts sits

The same service costs 3.7 times more in Alaska than in Delaware. Every bar is a state, most expensive first. Touch or drag across it to read any state, then open that state for its carriers and full range.

Massachusetts· 19th of 51

$182

AK $389DE $105

Median negotiated rate in each state, from every insurer that publishes one. States where no insurer publishes a rate for this service are not shown.