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Gene Test Guiding Chemotherapy Dosing

Illinois rates for HCPCS 81346

A laboratory test that examines one particular gene in a blood sample for specific known variations that change how the body handles a chemotherapy medicine. People carrying certain versions clear the medicine faster or slower than usual, which alters how much benefit and how much side effect a standard dose produces. The result helps the treating team set the dose or choose between medicines; it is not used to diagnose a condition.

Rates data updated October 2026.

How much does Gene Test Guiding Chemotherapy Dosing cost?

$174

Typical negotiated rate. In Illinois, October 2026.

Insurers have agreed to pay about $174 for this service. The price depends on where it is billed: about $145 from a physician practice, and about $363 from a hospital or other facility.

These are rates insurers have negotiated with providers, not the amount a patient is billed. What you owe depends on your plan's deductible and coinsurance. Based on rates published by 5 insurance carriers under federal price transparency rules.

Prices by location type

Billed byTypicalRange
Physician practiceA doctor's office, clinic or independent provider$145$105 to $204
FacilityA hospital or hospital-owned outpatient department$363$234 to $676

How much rates vary

Facilitymedian $363 · 10th to 90th $195 to $1,259Professionalmedian $145 · 10th to 90th $74 to $263
$10$50$200$1Kfacility $363professional $145

Distribution of negotiated rates across all payers (price axis is log-scale). Need provider-level prices or 24+ months of history? Contact us.

Rates by insurance carrier

Insurance Carrier
Aetna
Setting
Facility
Modifier
None
Typical Low
$144.54
Median
$281.84
Typical High
$524.81
Aetna
Setting
Facility
Modifier
52 · Reduced service
Typical Low
$72.44
Median
$138.04
Typical High
$263.03
Aetna
Setting
Facility
Modifier
53 · Discontinued
Typical Low
$28.84
Median
$54.95
Typical High
$104.71
Aetna
Setting
Professional
Modifier
None
Typical Low
$128.82
Median
$144.54
Typical High
$151.36
Aetna
Setting
Professional
Modifier
52 · Reduced service
Typical Low
$72.44
Median
$72.44
Typical High
$79.43
Aetna
Setting
Professional
Modifier
53 · Discontinued
Typical Low
$28.84
Median
$28.84
Typical High
$31.62
BCBS Illinois
Setting
Facility
Modifier
None
Typical Low
$208.93
Median
$302.00
Typical High
$2,187.76
Cigna
Setting
Facility
Modifier
None
Typical Low
$194.98
Median
$416.87
Typical High
$758.58
Cigna
Setting
Professional
Modifier
None
Typical Low
$79.43
Median
$204.17
Typical High
$288.40
Hally Health
Setting
Professional
Modifier
None
Typical Low
$173.78
Median
$234.42
Typical High
$346.74
Hally Health
Setting
Facility
Modifier
None
Typical Low
$100.00
Median
$100.00
Typical High
$100.00
Hally Health
Setting
Professional
Modifier
None
Typical Low
$229.09
Median
$229.09
Typical High
$229.09
United
Setting
Facility
Modifier
None
Typical Low
$173.78
Median
$208.93
Typical High
$218.78
United
Setting
Professional
Modifier
None
Typical Low
$74.13
Median
$104.71
Typical High
$173.78

Where Illinois sits

The same service costs 3.7 times more in Alaska than in Delaware. Every bar is a state, most expensive first. Touch or drag across it to read any state, then open that state for its carriers and full range.

Illinois· 22nd of 51

$174

AK $389DE $105

Median negotiated rate in each state, from every insurer that publishes one. States where no insurer publishes a rate for this service are not shown.