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Genetic Test For Thiopurine Drug Handling

Ohio rates for HCPCS 81335

A blood or saliva test that looks for common inherited changes in a gene controlling how the body breaks down a group of medicines used for leukemia, inflammatory bowel disease, and some autoimmune conditions. People carrying these changes clear the drug slowly and can develop dangerously low blood counts on a standard dose. The result is used to set a safe starting dose or to choose a different medicine.

Rates data updated July 2026.

How much does Genetic Test For Thiopurine Drug Handling cost?

$166

Typical negotiated rate. In Ohio, July 2026.

Insurers have agreed to pay about $166 for this service. The price depends on where it is billed: about $141 from a physician practice, and about $269 from a hospital or other facility. The two figures are alternatives, not parts of one bill.

These are rates insurers have negotiated with providers, not the amount a patient is billed. What you owe depends on your plan's deductible and coinsurance. Based on rates published by 8 insurance carriers under federal price transparency rules.

Where it's billed changes the price

Billed byTypicalRange
Physician practiceA doctor's office, clinic or independent provider$141$93.33 to $174
FacilityA hospital or hospital-owned outpatient department$269$182 to $437

How much rates vary

Facilitymedian $269 · 10th to 90th $158 to $617Professionalmedian $141 · 10th to 90th $69 to $355
$100$200$500facility $269professional $141

Distribution of negotiated rates across all payers (price axis is log-scale). Each curve is scaled to its own total: facility and professional rates are different services, shown together to compare where they cluster. Need provider-level prices or 24+ months of history? Contact us.

Rates by insurance carrier

Insurance Carrier
Aetna
Setting
Facility
Modifier
Global
Typical Low
$147.91
Median
$331.13
Typical High
$707.95
Aetna
Setting
Professional
Modifier
Global
Typical Low
$141.25
Median
$141.25
Typical High
$588.84
Anthem BCBS
Setting
Facility
Modifier
Global
Typical Low
$158.49
Median
$186.21
Typical High
$323.59
Anthem BCBS
Setting
Professional
Modifier
Global
Typical Low
$69.18
Median
$91.20
Typical High
$234.42
CareSource
Setting
Facility
Modifier
Global
Typical Low
$199.53
Median
$199.53
Typical High
$199.53
CareSource
Setting
Professional
Modifier
Global
Typical Low
$234.42
Median
$234.42
Typical High
$234.42
Cigna
Setting
Facility
Modifier
Global
Typical Low
$169.82
Median
$229.09
Typical High
$891.25
Cigna
Setting
Professional
Modifier
Global
Typical Low
$79.43
Median
$128.82
Typical High
$346.74
Medical Mutual of Ohio
Setting
Facility
Modifier
Global
Typical Low
$186.21
Median
$229.09
Typical High
$977.24
Medical Mutual of Ohio
Setting
Professional
Modifier
Global
Typical Low
$79.43
Median
$128.82
Typical High
$331.13
Molina
Setting
Professional
Modifier
Global
Typical Low
$120.23
Median
$158.49
Typical High
$190.55
SummaCare
Setting
Professional
Modifier
Global
Typical Low
$147.91
Median
$208.93
Typical High
$407.38
United
Setting
Facility
Modifier
Global
Typical Low
$104.71
Median
$173.78
Typical High
$263.03
United
Setting
Professional
Modifier
Global
Typical Low
$74.13
Median
$104.71
Typical High
$234.42

Where Ohio sits

The same service costs 3.3 times more in Alaska than in Delaware. Every bar is a state, most expensive first. Touch or drag across it to read any state, then open that state for its carriers and full range.

Ohio· 32nd of 51

$166

AK $389DE $117

Median negotiated rate in each state, from every insurer that publishes one. States where no insurer publishes a rate for this service are not shown.